SCHEMBL31028

SCHEMBL31028

CC(C)(C)OC(=O)N1CCC(=O)CC1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
ESR2 Q92731 1/20 0.49
MAPT P10636 3/20 0.48
KDM4E B2RXH2 1/20 0.48
THRB P10828 1/20 0.48
NR1H2 P55055 1/20 0.48
HPGD P15428 1/20 0.47
DDB1 Q16531 1/20 0.47
CRBN Q96SW2 1/20 0.47
GPR119 Q8TDV5 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
RECQL P46063 1/20 0.45
EPHX1 P07099 1/20 0.45
ALDH1A1 P00352 2/20 0.44
NPC1 O15118 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27669441 1.00 USP2 (0.56) USP2SMN1; SMN2ESR2MAPTKDM4E
Ammonia Solution, Strong SCHEMBL27841683 0.98 USP2 (0.55) USP2SMN1; SMN2ESR2MAPTKDM4E
Iodomethane SCHEMBL15848230 0.96 USP2 (0.53) USP2SMN1; SMN2ESR2MAPTKDM4E
Ethylene SCHEMBL3832936 0.96 USP2 (0.53) USP2SMN1; SMN2ESR2MAPTKDM4E
SCHEMBL157123 0.93 HPGD (0.50) USP2SMN1; SMN2ESR2MAPTKDM4E
Ethylene Glycol SCHEMBL27346767 0.93 USP2 (0.50) USP2SMN1; SMN2ESR2MAPTKDM4E
SCHEMBL3616758 0.91 HPGD (0.53) USP2SMN1; SMN2ESR2MAPTKDM4E
SCHEMBL21128616 0.90 HPGD (0.55) USP2SMN1; SMN2ESR2MAPTKDM4E
SCHEMBL123032 0.89 ESR2 (0.54) USP2SMN1; SMN2ESR2MAPTKDM4E
SCHEMBL4181120 0.89 USP2 (0.53) USP2SMN1; SMN2ESR2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16744 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 EP claimed
EP-4041726-B1 PROCESS FOR THE PRODUCTION OF 5-(4-((2 S,5 S)-5-(4-CHLOROBENZYL)-2-METHYLMORPHOLINO)PIPERIDIN-1-YL)-1 H-1,2,4-TRIAZOL-3-AMINE MOLECURE SA (PL) 2025-09-17 EP claimed
CN-120060232-A N-BOC-piperidone reductase immobilization method 上海仁酶生物科技有限公司 2025-05-30 CN claimed
CN-119930651-A Thiazolopiperidine-containing derivative, and preparation method and application thereof 南开大学 2025-05-06 CN claimed
CN-117700405-B Preparation method of 6-fluoro-3-piperidin-4-yl-1, 2-benzisoxazole hydrochloride 山东康诺生物工程有限公司 2025-04-04 CN claimed
CN-119661529-A Synthesis method of 3, 9-diazaspiro [5.5] undecane-3-tert-butyl formate 上海馨远医药科技有限公司 2025-03-21 CN claimed
CN-119552168-A Preparation method of (R) -3-amino-1-oxa-8-azaspiro [4.5] decane-8-carboxylic acid tert-butyl ester 上海馨远医药科技有限公司 2025-03-04 CN claimed
CN-119431219-A Chiral 3-hydroxy-4-fluoropiperidine derivative and synthesis method thereof 诚达药业股份有限公司 2025-02-14 CN claimed
CN-114466845-B Method for preparing 5- (4- ((2S, 5S) -5- (4-chlorobenzyl) -2-methylmorpholino) piperidin-1-yl) -1H-1,2, 4-triazol-3-amine 昂科艾伦迪治疗法公司 2024-12-17 CN claimed
CN-118994102-A Efluorconazole derivatives and antifungal activity thereof 张小宇 2024-11-22 CN claimed
US-7034041-B2 Substituted 4-phenyl-1-(1-phenylcyclohexyl)-1,2,3,6-tetrahydropyridine GRUENENTHAL GMBH (DE) 2006-04-25 US claimed
EP-1436284-B1 SYNTHESIS OF 4- (Z)-(4-BROMOPHENYL)(ETHOXYIMINO)METHYL]-1'- 2,4-DIMETHYL-1-OXIDO-3-PYRIDINYL)CARBONYL]-4'METHYL-1,4'BIPIPERIDINE SCHERING CORP (US) 2005-08-03 EP claimed
US-20050104233-A1 Method of substituent introduction through halogen-metal exchange reaction BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-05-19 US claimed
EP-1510510-A1 METHOD OF SUBSTITUENT INTRODUCTION THROUGH HALOGEN-METAL EXCHANGE REACTION BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-03-02 EP claimed
US-6818773-B2 AIDS THERAPY; ANTIINFLAMAMTORY AGENTS; ANTIALLERGENS; RHEUMATIC DISEASES SCHERING CORPORATION 2004-11-16 US claimed
EP-1436284-A1 SYNTHESIS OF 4- (Z)-(4-BROMOPHENYL)(ETHOXYIMINO)METHYL]-1'- 2,4-DIMETHYL-1-OXIDO-3-PYRIDINYL)CARBONYL]-4'METHYL-1,4'BIPIPERIDINE SCHERING CORPORATION (US) 2004-07-14 EP claimed
WO-2003033490-A9 SYNTHESIS OF 4-[(Z)-(4-BROMOPHENYL)(ETHOXYIMINO)METHYL]-1'-[2,4-DIMETHYL-1-OXIDO-3-PYRIDINYL)CARBONYL]-4'METHYL-1,4'BIPIPERIDINE SCHERING CORP (US) 2004-06-10 WO claimed
US-20030225116-A1 Substituted 4-phenyl-1-(1-phenylcyclohexyl)-1,2,3,6-tetrahydropyridine GRUENENTAL GMBH (DE) 2003-12-04 US claimed
US-20030105131-A1 Synthesis of 4-[(Z)-4-bromophenyl)(ethoxyimino) methyl]-1'-[(2,4-dimethyl-1-oxido-3-pyridinyl)carbonyl]-4'-methyl-1,4-'bipiperidine SCHERING CORPORATION 2003-06-05 US claimed
WO-2003033490-A1 SYNTHESIS OF 4-[(Z)-(4-BROMOPHENYL)(ETHOXYIMINO)METHYL]-1'-[2,4-DIMETHYL-1-OXIDO-3-PYRIDINYL)CARBONYL]-4'METHYL-1,4'BIPIPERIDINE SCHERING CORPORATION (US) 2003-04-24 WO claimed