SCHEMBL12304263

SCHEMBL12304263

Cc1ccc2nc(-c3ccc(-c4nc5ccccc5o4)c4ccccc34)oc2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.62
HPGD P15428 9/20 0.62
ALDH1A1 P00352 8/20 0.62
MAPT P10636 7/20 0.62
TDP1 Q9NUW8 2/20 0.62
USP2 O75604 2/20 0.62
HSD17B10 Q99714 5/20 0.60
NPC1 O15118 9/20 0.58
RAB9A P51151 9/20 0.58
SMN1; SMN2 Q16637 8/20 0.58
TP53 P04637 3/20 0.58
PKM P14618 2/20 0.58
ESR1 P03372 4/20 0.56
ESR2 Q92731 4/20 0.56
RPS6KA3 P51812 1/20 0.53
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12304267 0.95 HSD17B10 (0.66) KDM4EHPGDALDH1A1MAPTTDP1
SCHEMBL13620843 0.91 KDM4E (0.63) KDM4EHPGDALDH1A1MAPTTDP1
SCHEMBL12304269 0.90 HSD17B10 (0.54) KDM4EHPGDALDH1A1MAPTTDP1
SCHEMBL30498604 0.86 KDM4E (0.69) KDM4EHPGDALDH1A1MAPTTDP1
SCHEMBL13620844 0.86 KDM4E (0.69) KDM4EHPGDALDH1A1MAPTTDP1
SCHEMBL29627559 0.85 ALDH1A1 (0.65) KDM4EHPGDALDH1A1MAPTTDP1
SCHEMBL30096340 0.85 ALDH1A1 (0.65) KDM4EHPGDALDH1A1MAPTTDP1
SCHEMBL30682 0.85 ALDH1A1 (0.65) KDM4EHPGDALDH1A1MAPTTDP1
SCHEMBL10039086 0.84 KDM4E (0.67) KDM4EHPGDALDH1A1MAPTTDP1
SCHEMBL19601392 0.84 NPC1 (0.72) KDM4EHPGDALDH1A1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293150-B2 Near-infrared absorbing material FUJIFILM CORPORATION (JP) 2012-10-23 US disclosed
US-8021573-B2 Oxidized N,N*-[-(4-amino)diphenyl]-p-phenylenediamine derivatives or dimmonium salt; di-benzoxazole or chromene derivative as luminescent agent; light resistance, discoloration inhibition; optical filters and recording media FUJIFILM CORPORATION (JP) 2011-09-20 US disclosed
US-7875215-B2 A singlet oxygen scavenger, a radical trapping agent and an antioxidant; quaternary or amine salt derivatives of 4-hydroxy-3-cyclopenten-1,-2-dione; discoloration inhibition, light resistance; electrooptics, liquid crystal display, optical cards, optical recording media, and protective goggles FUJIFILM CORPORATION (JP) 2011-01-25 US disclosed
US-20100224839-A1 NEAR-INFRARED ABSORBING MATERIAL FUJIFILM CORPORATION (JP) 2010-09-09 US disclosed
US-20080073626-A1 A singlet oxygen scavenger, a radical trapping agent and an antioxidant; quaternary or amine salt derivatives of 4-hydroxy-3-cyclopenten-1,-2-dione; discoloration inhibition, light resistance; electrooptics, liquid crystal display, optical cards, optical recording media, and protective goggles FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20080067479-A1 NEAR-INFRARED-ABSORBING MATERIAL AND NEAR-INFRARED-ABSORBING FILTER FUJIFILM CORPORATION (JP) 2008-03-20 US disclosed