Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 17/20 | 0.63 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.62 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13559323 | 0.90 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL14549941 | 0.90 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL14330732 | 0.88 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAEPHX2 | |
| SCHEMBL14549933 | 0.88 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAEPHX2 | |
| SCHEMBL14719987 | 0.84 | FOLH1 (0.74) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL14720004 | 0.84 | FOLH1 (0.74) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL19788064 | 0.84 | FOLH1 (0.49) | FOLH1NAALAD2RIMKLAEPHX2 | |
| SCHEMBL18253627 | 0.84 | FOLH1 (0.49) | FOLH1NAALAD2RIMKLAEPHX2 | |
| SCHEMBL13559304 | 0.84 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL19360000 | 0.83 | FOLH1 (0.74) | FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237686-A1 | FORMULATIONS AND METHODS OF USE | CERULEAN PHARMA INC (US) | 2011-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237686-A1 | FORMULATIONS AND METHODS OF USE | LPXN, LIPA, CHMP4B | FOLH1 978/4885NAALAD2 2773/4885RIMKLA 2818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.