Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 10/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18253627 | 1.00 | FOLH1 (0.49) | FOLH1SMN1; SMN2FPR2EPHX1LMNA | |
| SCHEMBL12304382 | 0.84 | FOLH1 (0.63) | FOLH1RIMKLANAALAD2EPHX2 | |
| SCHEMBL18538622 | 0.80 | FPR2 (0.47) | FOLH1SMN1; SMN2FPR2EPHX1RIMKLA | |
| SCHEMBL31490542 | 0.80 | SMN1; SMN2 (0.53) | FOLH1SMN1; SMN2EPHX1LMNAEPHX2 | |
| SCHEMBL18538620 | 0.79 | FOLH1 (0.48) | FOLH1SMN1; SMN2FPR2EPHX1EPHX2 | |
| SCHEMBL19359997 | 0.78 | FOLH1 (0.47) | FOLH1SMN1; SMN2FPR2EPHX1LMNA | |
| SCHEMBL12216484 | 0.77 | EPHX1 (0.61) | FOLH1SMN1; SMN2EPHX1EPHX2NOD1 | |
| SCHEMBL17615103 | 0.77 | FPR2 (0.44) | FOLH1SMN1; SMN2FPR2RIMKLANAALAD2 | |
| SCHEMBL17190062 | 0.75 | FOLH1 (0.61) | FOLH1SMN1; SMN2RIMKLANAALAD2EPHX2 | |
| SCHEMBL15762838 | 0.75 | FOLH1 (0.61) | FOLH1SMN1; SMN2RIMKLANAALAD2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872913-B2 | Drug loaded polymeric nanoparticles and methods of making and using same | PFIZER INC. (US) | 2018-01-23 | — | — | US | disclosed |