Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | BLM | P54132 | 2/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | THPO | P40225 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17266372 | 0.86 | MAPT (0.66) | MAPTALDH1A1HSD17B10KDM4EHIF1A | |
| SCHEMBL30446328 | 0.85 | MAPT (0.73) | MAPTALDH1A1HSD17B10KDM4EHIF1A | |
| SCHEMBL400288 | 0.85 | MAPT (0.73) | MAPTALDH1A1HSD17B10KDM4EHIF1A | |
| SCHEMBL30616852 | 0.82 | MAPT (1.00) | MAPTALDH1A1HSD17B10KDM4EHIF1A | |
| SCHEMBL328568 | 0.82 | MAPT (1.00) | MAPTALDH1A1HSD17B10KDM4EHIF1A | |
| SCHEMBL14164293 | 0.81 | ERCC1 (0.57) | MAPTALDH1A1HSD17B10KDM4EHIF1A | |
| Water SCHEMBL1321161 | 0.81 | MAPT (0.97) | MAPTALDH1A1HSD17B10KDM4EHIF1A | |
| Hydrochloric Acid SCHEMBL28839145 | 0.81 | MAPT (0.97) | MAPTALDH1A1HSD17B10KDM4EHIF1A | |
| Potassium SCHEMBL29870134 | 0.81 | MAPT (0.97) | MAPTALDH1A1HSD17B10KDM4EHIF1A | |
| SCHEMBL29870429 | 0.81 | MAPT (0.97) | MAPTALDH1A1HSD17B10KDM4EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110218158-A1 | DNA CYTOSINE DEAMINASE INHIBITORS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2011-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218158-A1 | DNA CYTOSINE DEAMINASE INHIBITORS | DCTD, APOBEC3A, UNG | MAPT 4260/4885ALDH1A1 795/4885HSD17B10 1581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.