SCHEMBL328568

SCHEMBL328568

CC(=O)NCCc1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 1.00
KDM4E B2RXH2 3/20 1.00
HSD17B10 Q99714 3/20 1.00
HIF1A Q16665 2/20 1.00
ALDH1A1 P00352 2/20 1.00
LMNA P02545 2/20 1.00
HPGD P15428 2/20 1.00
BLM P54132 2/20 1.00
PTGS1 P23219 1/20 1.00
PTGS2 P35354 4/20 0.70
JAK3 P52333 1/20 0.70
F13A1 P00488 1/20 0.66
TP53 P04637 1/20 0.62
CYP1A2 P05177 1/20 0.62
ALOX15 P16050 1/20 0.62
TSHR P16473 1/20 0.62
NFKB1 P19838 1/20 0.62
MAPK1 P28482 1/20 0.62
THPO P40225 1/20 0.62
SMN1; SMN2 Q16637 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30616852 1.00 MAPT (1.00) MAPTKDM4EHSD17B10HIF1AALDH1A1
Bromide SCHEMBL28839154 0.98 MAPT (0.97) MAPTKDM4EHSD17B10HIF1AALDH1A1
Potassium SCHEMBL29870134 0.98 MAPT (0.97) MAPTKDM4EHSD17B10HIF1AALDH1A1
Water SCHEMBL1321161 0.98 MAPT (0.97) MAPTKDM4EHSD17B10HIF1AALDH1A1
SCHEMBL29870429 0.98 MAPT (0.97) MAPTKDM4EHSD17B10HIF1AALDH1A1
Hydrochloric Acid SCHEMBL28839145 0.98 MAPT (0.97) MAPTKDM4EHSD17B10HIF1AALDH1A1
Acetic Acid SCHEMBL28839867 0.97 MAPT (0.93) MAPTKDM4EHSD17B10HIF1AALDH1A1
Phosphoric Acid SCHEMBL28952898 0.94 MAPT (0.88) MAPTKDM4EHSD17B10HIF1AALDH1A1
Formic Acid SCHEMBL28839111 0.94 MAPT (0.88) MAPTKDM4EHSD17B10HIF1AALDH1A1
Sulfuric Acid SCHEMBL28839069 0.94 MAPT (0.88) MAPTKDM4EHSD17B10HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12403719-B2 Efficient ink erasure system SOCIéTé BIC (FR) 2025-09-02 US claimed
CN-118294579-B Method for identifying metabolites and non-target metabonomics combined supervision and study of Boea chenopodii honey 中国农业科学院蜜蜂研究所 2025-02-18 CN claimed
CN-119265237-A Method for improving silk performance by combining gene operation with in-vitro and in-vivo combined action of physicochemical treatment 浙江超丝生物科技有限公司 2025-01-07 CN claimed
CN-118325376-A Antimicrobial coating and preparation method and application thereof 泛领生物医学技术(苏州)有限公司 2024-07-12 CN claimed
US-20240227430-A1 EFFICIENT INK ERASURE SYSTEM SOCIéTé BIC (FR) 2024-07-11 US claimed
CN-118294579-A Method for identifying metabolites and non-target metabonomics combined supervision and study of Boea chenopodii honey 中国农业科学院蜜蜂研究所 2024-07-05 CN claimed
CN-115290768-B Method for detecting effective components of pediatric Qixing tea particles 广州中医药大学(广州中医药研究院) 2024-06-11 CN claimed
CN-115290769-B Method for detecting effective components of pediatric Qixing tea particles 广州中医药大学(广州中医药研究院) 2024-05-14 CN claimed
EP-4330052-A1 EFFICIENT INK ERASURE SYSTEM Société BIC (FR) 2024-03-06 EP claimed
CN-117304162-A Novel cicada slough acetyldopamine trimer with anti-inflammatory activity and preparation method and application thereof 江苏省中医药研究院 2023-12-29 CN claimed
US-20160090489-A1 SURFACE TREATMENT COMPOSITON FOR FORMING SELF-ASSEMBLED COATING CAPABLE OF BEING EASILY COATED, REMOVED OR RECOATED POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) 2016-03-31 US claimed
CN-102285958-A Dopamine polymer as well as derivative, preparation method and medicinal purpose thereof 2011-12-21 CN claimed
US-20080234385-A1 N-acetyl dopamine derivatives or N-alkyldopamine derivatives and a pharmaceutically acceptable carrier for treating a cell, preferably in an animal or human suffering from overexpression or abundant TNF-alpha CARITAS ST. ELIZABETH'S MEDICAL CENTER (US) 2008-09-25 US claimed
US-20080200557-A1 Method for Inhibiting Lipid Peroxidation CARITAS ST. ELIZABETH HOSPITAL OF BOSTON, INC. (US) 2008-08-21 US claimed
WO-2007016214-A2 METHOD FOR INHIBITING TNF-ALPHA CARITAS ST. ELIZABETH'S MEDICAL CENTER (US) 2007-02-08 WO claimed
WO-2006014507-A2 METHOD FOR INHIBITING LIPID PEROXIDATION CARITAS ST. ELIZABETH HOSPITAL OF BOSTON, INC. (US) 2006-02-09 WO claimed
US-20040261198-A1 Restructuring and finishing of keratin fibers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2004-12-30 US claimed
EP-1477165-A2 Blocking induction of tetrahydrobiopterin to block induction of nitric oxide synthesis Cornell Research Foundation, INC. (US) 2004-11-17 EP claimed
US-4453941-A Composition and process for producing pigmentation in hair or skin BOARD OF OVERSEERS OF GOSHEN COLLEGE (US) 1984-06-12 US claimed
US-4390341-A Composition and process for producing pigmentation in hair or skin BOARD OF OVERSEERS OF GOSHEN COLLEGE (US) 1983-06-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200557-A1 Method for Inhibiting Lipid Peroxidation AANAT, LPO, GPX4 MAPT 3653/4885KDM4E 4727/4885HSD17B10 231/4885
US-20080234385-A1 N-acetyl dopamine derivatives or N-alkyldopamine derivatives and a pharmaceutically acceptable carrier for treating a cell, preferably in an animal or human suffering from overexpression or abundant TNF-alpha AANAT, TNF, SLC6A3 MAPT 1888/4885KDM4E 4780/4885HSD17B10 1444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.