SCHEMBL123067

SCHEMBL123067

Cc1cc(Cl)cc(C(=O)O)c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C2 P52895 4/20 0.64
AKR1C1 Q04828 4/20 0.64
AKR1C4 P17516 1/20 0.64
AKR1C3 P42330 1/20 0.64
ALDH1A1 P00352 4/20 0.58
HPGD P15428 3/20 0.58
HSD17B10 Q99714 3/20 0.58
HMGB1 P09429 1/20 0.58
CXCL12 P48061 1/20 0.58
KDM4E B2RXH2 2/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CTH P32929 1/20 0.47
CYP3A4 P08684 2/20 0.47
BCL2L1 Q07817 1/20 0.47
TP53 P04637 1/20 0.45
NOTUM Q6P988 1/20 0.44
PHLPP2 Q6ZVD8 1/20 0.44
MYC P01106 1/20 0.43
NR4A1 P22736 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30810288 1.00 AKR1C2 (0.64) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL29495446 0.83 BCL2L1 (0.50) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL10469179 0.83 BCL2L1 (0.50) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL10373451 0.82 BCL2L1 (0.46) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL11866049 0.82 BCL2L1 (0.46) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL8148635 0.81 CYP3A4 (0.59) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL27705723 0.81 AKR1C4 (0.50) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL1812602 0.79 ALDH1A1 (0.48) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL6175638 0.79 AKR1C2 (0.64) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1
SCHEMBL27628974 0.79 BCL2L1 (0.40) AKR1C2AKR1C1AKR1C4AKR1C3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0009636-B1 3-CHLORO-6-HYDROXY-5-METHYLBENZOIC ACID DERIVATIVES, CORRESPONDING PHARMACEUTICAL PREPARATIONS, GROWTH PROMOTING COMPOSITIONS, THE USE OF THE COMPOUNDS FOR PROMOTING GROWTH IN CERTAIN ANIMALS AND THEIR MANUFACTURE F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1982-06-02 EP claimed
EP-0009636-A2 3-Chloro-6-hydroxy-5-methylbenzoic acid derivatives, corresponding pharmaceutical preparations, growth promoting compositions, the use of the compounds for promoting growth in certain animals and their manufacture F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-04-16 EP claimed
EP-4583870-A2 MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER Mito Biopharma, LLC (US) 2025-07-16 EP disclosed
WO-2024054766-A2 MITOCHONDRIAL UNCOUPLERS FOR TREATMENT OF METABOLIC DISEASES AND CANCER MITO BIOPHARMA, LLC (US) 2024-03-14 WO disclosed
CN-111200935-A Dicamba compositions with reduced spray drift potential 美国陶氏益农公司 2020-05-26 CN disclosed
US-20190116788-A1 DICAMBA COMPOSITIONS WITH REDUCED SPRAY DRIFT POTENTIAL DOW AGROSCIENCES LLC (US) 2019-04-25 US disclosed
US-20190116788-A1 DICAMBA COMPOSITIONS WITH REDUCED SPRAY DRIFT POTENTIAL DOW AGROSCIENCES LLC (US) 2019-04-25 US disclosed
WO-2019079236-A1 DICAMBA COMPOSITIONS WITH REDUCED SPRAY DRIFT POTENTIAL DOW AGROSCIENCES LLC (US) 2019-04-25 WO disclosed
WO-2019079236-A1 DICAMBA COMPOSITIONS WITH REDUCED SPRAY DRIFT POTENTIAL DOW AGROSCIENCES LLC (US) 2019-04-25 WO disclosed
EP-3026046-A1 THIAZOLES AS CANNABINOID RECEPTOR LIGANDS AbbVie Inc. (US) 2016-06-01 EP disclosed
EP-2376462-B1 THIAZOLES AS CANNABINOID RECEPTOR LIGANDS ABBVIE INC (US) 2015-12-16 EP disclosed
US-4000130-A INDOLE DYES, POLYACRYLONITRILE BAYER AKTIENGESELLSCHAFT (DT) 1976-12-28 US disclosed
US-4000141-A SUBSTITUTED TETRAHYDRO QUINOLINE CATIONIC DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-12-28 US disclosed
US-3992405-A ESPECIALLY FOR DYEING POLYACRYLIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1976-11-16 US disclosed
US-3991042-A Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus BAYER AKTIENGESELLSCHAFT (DT) 1976-11-09 US disclosed
US-3971807-A BENZINDOLE BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed
US-3959310-A BENZINDOLE BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US disclosed
US-3950347-A NAPHTHOLACTAM DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-04-13 US disclosed
US-3948877-A POLYACRYLONITRILE, ACID MODIFIED POLYESTERS OR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190116788-A1 DICAMBA COMPOSITIONS WITH REDUCED SPRAY DRIFT POTENTIAL DDT, CDA, SGMS1 AKR1C2 3685/4885AKR1C1 3661/4885AKR1C4 3249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.