Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.60 |
| ▸ | RAB9A | P51151 | 10/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12306756 | 0.97 | NPC1 (0.60) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL1421139 | 0.95 | S1PR1 (0.58) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL30083 | 0.95 | NPC1 (0.62) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL12354585 | 0.92 | S1PR1 (0.61) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL10330370 | 0.91 | NPC1 (0.64) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL12570671 | 0.89 | NPC1 (0.64) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL31606600 | 0.89 | NPC1 (0.64) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL74782 | 0.89 | S1PR1 (0.67) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| Biphenyl SCHEMBL28899764 | 0.89 | S1PR1 (0.67) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 | |
| SCHEMBL2623779 | 0.89 | S1PR1 (0.67) | NPC1RAB9AKDM4ES1PR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8475939-B2 | m-terphenyl compound derivatives and application for organic light emitting diode | NATIONAL TSING HUA UNIVERSITY (TW) | 2013-07-02 | — | — | US | disclosed |
| US-8475939-B2 | m-terphenyl compound derivatives and application for organic light emitting diode | NATIONAL TSING HUA UNIVERSITY (TW) | 2013-07-02 | — | — | US | disclosed |
| US-20110220880-A1 | m-TERPHENYL COMPOUND DERIVATIVES AND APPLICATION FOR ORGANIC LIGHT EMITTING DIODE | E INK HOLDINGS INC. (TW) | 2011-09-15 | — | — | US | disclosed |
| US-20110220880-A1 | m-TERPHENYL COMPOUND DERIVATIVES AND APPLICATION FOR ORGANIC LIGHT EMITTING DIODE | E INK HOLDINGS INC. (TW) | 2011-09-15 | — | — | US | disclosed |
| WO-2010045263-A2 | PRINTABLE LIGHT-EMITTING COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2010-04-22 | — | — | WO | disclosed |
| WO-2009006550-A1 | LIGHT EMITTING DEVICES AND COMPOSITIONS | NITTO DENKO CORPORATION (JP) | 2009-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110220880-A1 | m-TERPHENYL COMPOUND DERIVATIVES AND APPLICATION FOR ORGANIC LIGHT EMITTING DIODE | CLTB, CYBA, C5 | NPC1 425/4885RAB9A 2484/4885KDM4E 4240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.