Biphenyl

Biphenyl

SCHEMBL28899764

CC(C)(C)c1ccc(-c2nnc(-c3ccc(-c4ccccc4)cc3)o2)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.67
NPC1 O15118 13/20 0.64
RAB9A P51151 13/20 0.64
KDM4E B2RXH2 4/20 0.64
SMN1; SMN2 Q16637 7/20 0.63
HPGD P15428 6/20 0.61
POLB P06746 2/20 0.61
NFKB1 P19838 1/20 0.61
NFKB2 Q00653 1/20 0.61
RELA Q04206 1/20 0.61
TP53 P04637 2/20 0.60
EGFR P00533 1/20 0.60
ALDH1A1 P00352 4/20 0.59
GLA P06280 1/20 0.59
MAPT P10636 1/20 0.59
ALOX15 P16050 1/20 0.59
HSD17B10 Q99714 1/20 0.59
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
NR1H4 Q96RI1 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2623779 1.00 S1PR1 (0.67) S1PR1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL74782 1.00 S1PR1 (0.67) S1PR1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL28982567 1.00 S1PR1 (0.67) S1PR1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL8385439 1.00 S1PR1 (0.67) S1PR1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL36912 1.00 S1PR1 (0.67) S1PR1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL2839508 0.98 S1PR1 (0.69) S1PR1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL1104799 0.92 NPC1 (0.72) S1PR1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL6296907 0.92 NPC1 (0.72) S1PR1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL1421139 0.92 S1PR1 (0.58) S1PR1NPC1RAB9AKDM4ESMN1; SMN2
SCHEMBL12354585 0.91 S1PR1 (0.61) S1PR1NPC1RAB9AKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111606812-B Triarylamine derivative and organic electroluminescent device thereof 长春海谱润斯科技股份有限公司 2021-07-06 CN disclosed
CN-111606812-A Triarylamine derivative and organic electroluminescent device thereof 长春海谱润斯科技有限公司 2020-09-01 CN disclosed