Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.74 |
| ▸ | THRB | P10828 | 8/20 | 0.74 |
| ▸ | BLM | P54132 | 7/20 | 0.74 |
| ▸ | RECQL | P46063 | 6/20 | 0.74 |
| ▸ | TOP2A | P11388 | 5/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | BRCA1 | P38398 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.74 |
| ▸ | HTT | P42858 | 4/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.74 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.74 |
| ▸ | FYN | P06241 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leurubicin SCHEMBL1795537 | 1.00 | MEN1 (0.74) | MEN1KMT2ATHRBBLMRECQL | |
| Leurubicin SCHEMBL29412217 | 1.00 | MEN1 (0.74) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL1792990 | 0.94 | MEN1 (0.72) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL9174521 | 0.94 | MEN1 (0.78) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL9175600 | 0.94 | MEN1 (0.78) | MEN1KMT2ATHRBBLMRECQL | |
| Hydrochloric Acid SCHEMBL1795063 | 0.93 | MEN1 (0.73) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL9173911 | 0.93 | MEN1 (0.76) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL6130215 | 0.92 | MEN1 (0.73) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL16137956 | 0.92 | MEN1 (0.72) | MEN1KMT2ATHRBBLMRECQL | |
| SCHEMBL9172273 | 0.91 | MEN1 (0.72) | MEN1KMT2ATHRBBLMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105457038-A | Quick release type medicine phosphatide compound and medicine composition thereof | UNIV SOUTHEAST | 2016-04-06 | — | — | CN | claimed |
| EP-2961730-A2 | METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS | XenoPort, Inc. (US) | 2016-01-06 | — | — | EP | claimed |
| US-20150158809-A9 | METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS | XENOPORT, INC. (US) | 2015-06-11 | — | — | US | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| WO-2014134005-A2 | METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS | XENOPORT, INC. (US) | 2014-09-04 | — | — | WO | claimed |
| US-20140243544-A1 | METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS | XENOPORT, INC. (US) | 2014-08-28 | — | — | US | claimed |
| CN-101486668-B | Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof | XENOPORT INC | 2014-07-02 | — | — | CN | claimed |
| US-8404287-B2 | Use of Fructus schisandrae and extracts thereof in preventing and decreasing toxic and side effects of antineoplastic drugs | ZHE JIANG DINGHUI PHARM CO. LTD. (CN) | 2013-03-26 | — | — | US | claimed |
| US-8299291-B2 | Methods of synthesizing 1-(acyloxy)-alkyl carbamate prodrugs | XENOPORT, INC. (US) | 2012-10-30 | — | — | US | claimed |
| US-8062870-B2 | Enantiomerically resolving acyloxyalkyl thiocarbonates used in synthesizing acyloxyalkyl carbamate prodrugs | XENOPORT, INC. (US) | 2011-11-22 | — | — | US | claimed |
| CN-1733302-A | Anticancer implantation agent | KONG QINGZHONG (CN) | 2006-02-15 | — | — | CN | claimed |
| CN-1686544-A | Anti entity tumour medicinal composition containing plant alkaloid | SHANDONG LANJIN BIOLOG ENGINEE (CN) | 2005-10-26 | — | — | CN | claimed |
| CN-1686552-A | Anti-solid tumor pharmaceutical composition containing topoisomerase inhibitor | SHANDONG LANJIN BIOLOG ENGINEE (CN) | 2005-10-26 | — | — | CN | claimed |
| CN-1686551-A | Anti-solid tumor pharmaceutical composition | SHANDONG LANJIN BIOLOG ENGINEE (CN) | 2005-10-26 | — | — | CN | claimed |
| CN-1679936-A | Anticarcinogen composition | LANJIN BIOLOG ENGINEERING CO L (CN) | 2005-10-12 | — | — | CN | claimed |
| CN-1679945-A | Anticarcinogen composition | LANJIN BIOLOG ENGINEERING CO L (CN) | 2005-10-12 | — | — | CN | claimed |
| CN-1634583-A | Anti-cancer medicine composition containing antineoplastic antibiotics | SHANDONG LANJIN BIOENGINEERING (CN) | 2005-07-06 | — | — | CN | claimed |
| CN-1634585-A | Anti-cancer medicine composition | SHANDONG LANJIN BIOENGINEERING (CN) | 2005-07-06 | — | — | CN | claimed |
| CN-1616099-A | Anti-cancer medicine composition | KONG QINGZHONG (CN) | 2005-05-18 | — | — | CN | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150158809-A9 | METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS | CPS1, CA7, NAAA | MEN1 227/4885KMT2A 741/4885THRB 3558/4885 |
| US-20140243544-A1 | METHOD OF MAKING 1-(ACYLOXY)-ALKYL CARBAMATE COMPOUNDS | CPS1, CA7, NAAA | MEN1 227/4885KMT2A 741/4885THRB 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.