SCHEMBL12320086

SCHEMBL12320086

Fc1c(F)c(F)c2[nH]cnc2c1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 3/20 0.43
CSNK2A2 P19784 2/20 0.43
MEN1 O00255 1/20 0.43
RAB9A P51151 1/20 0.43
CSNK2B P67870 1/20 0.43
KMT2A Q03164 1/20 0.43
DYRK1A Q13627 1/20 0.43
CSNK2A3 Q8NEV1 1/20 0.43
ALDH1A1 P00352 2/20 0.36
PDPK1 O15530 2/20 0.35
PARP1 P09874 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
PTGS1 P23219 1/20 0.33
HBB P68871 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CHEK1 O14757 1/20 0.33
PI4KA P42356 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6309089 0.75 CSNK2A1 (0.39) CSNK2A1CSNK2A2MEN1RAB9ACSNK2B
SCHEMBL824416 0.72 CSNK2A1 (0.55) CSNK2A1CSNK2A2MEN1RAB9ACSNK2B
SCHEMBL22857644 0.69 ALDH1A1 (0.40) ALDH1A1PDPK1PARP1CHEK1ABL1
SCHEMBL15800772 0.68 PARP1 (0.46) CSNK2A1CSNK2A2MEN1RAB9ACSNK2B
SCHEMBL22566981 0.68 CSNK2A1 (0.41) CSNK2A1CSNK2A2MEN1RAB9ACSNK2B
SCHEMBL12846132 0.66 PDPK1 (0.34) CSNK2A1CSNK2A2MEN1RAB9ACSNK2B
SCHEMBL6956986 0.65 MAPT (0.46) MEN1KMT2AALDH1A1PARP1TDP1
SCHEMBL6956994 0.65 MAPT (0.41) CSNK2A1CSNK2A2MEN1RAB9ACSNK2B
SCHEMBL1967365 0.65 PARP1 (0.39) CSNK2A1CSNK2A2MEN1RAB9ACSNK2B
SCHEMBL12573417 0.65 CSNK2A1 (0.39) CSNK2A1CSNK2A2MEN1RAB9ACSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11552266-B2 Electrodes for electronic devices comprising an organic semiconducting layer FLEXENABLE LIMITED (GB) 2023-01-10 US disclosed
WO-2022165198-A1 THERAPEUTIC COMPOUNDS AND USES THEREOF BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2022-08-04 WO disclosed
US-20200274086-A1 ELECTRODES FOR ELECTRONIC DEVICES COMPRISING AN ORGANIC SEMICONDUCTING LAYER FLEXENABLE LIMITED (GB) 2020-08-27 US disclosed
WO-2019052978-A1 ELECTRODES FOR ELECTRONIC DEVICES COMPRISING AN ORGANIC SEMICONDUCTING LAYER MERCK PATENT GMBH (DE) 2019-03-21 WO disclosed
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-03-01 US disclosed
EP-3279997-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS SECONDARY BATTERY Asahi Kasei Kabushiki Kaisha (JP) 2018-02-07 EP disclosed
US-8878165-B2 Electrode treatment process for organic electronic devices MERCK PATENT GMBH (DE) 2014-11-04 US disclosed
US-20120319097-A1 ELECTRODE TREATMENT PROCESS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-12-20 US disclosed
WO-2011103952-A1 ELECTRODE TREATMENT PROCESS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-09-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180062213-A1 Nonaqueous Electrolyte and Nonaqueous Secondary Battery BPTF, BRD4, KCNN2 CSNK2A1 1101/4885CSNK2A2 1165/4885MEN1 1058/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.