Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.51 |
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17090854 | 0.85 | IDO1 (0.54) | SLC6A4IDO1PIN1 | |
| SCHEMBL12320494 | 0.83 | SLC6A4 (0.51) | SLC6A4IDO1PIN1HTR2CHTR2B | |
| SCHEMBL12320929 | 0.83 | SLC6A4 (0.55) | SLC6A4IDO1NPC1HTR2CHTR2B | |
| SCHEMBL12320500 | 0.80 | IDO1 (0.45) | SLC6A4IDO1PIN1 | |
| SCHEMBL12320928 | 0.76 | IDO1 (0.54) | SLC6A4IDO1PIN1 | |
| SCHEMBL8635407 | 0.75 | IDO1 (0.43) | SLC6A4IDO1PIN1 | |
| SCHEMBL1746749 | 0.74 | IDO1 (0.49) | SLC6A4IDO1PIN1 | |
| SCHEMBL12320178 | 0.74 | IDO1 (0.51) | SLC6A4IDO1PIN1 | |
| SCHEMBL11234063 | 0.73 | IDO1 (0.54) | SLC6A4IDO1PIN1 | |
| SCHEMBL12320212 | 0.72 | IDO1 (0.43) | SLC6A4IDO1PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368876-A1 | Derivatives of aminoindanes, their preparation and their application in therapeutics | SANOFI (FR) | 2011-09-28 | — | — | EP | disclosed |