Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.49 |
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8637973 | 0.88 | FFAR1 (0.49) | IDO1FFAR1PIN1 | |
| SCHEMBL12017975 | 0.86 | IDO1 (0.61) | IDO1FFAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21142124 | 0.83 | IDO1 (0.54) | IDO1FFAR1PRCPSLC6A2SLC6A4 | |
| SCHEMBL8529487 | 0.83 | IDO1 (0.54) | IDO1FFAR1CYP11B2PIN1PDPK1 | |
| SCHEMBL11335277 | 0.82 | SIGMAR1 (0.51) | IDO1FFAR1HTR1ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11571081 | 0.81 | SIGMAR1 (0.50) | IDO1FFAR1HTR1ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11571088 | 0.81 | SIGMAR1 (0.50) | IDO1FFAR1HTR1ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11571085 | 0.81 | SIGMAR1 (0.50) | IDO1FFAR1HTR1ASLC6A2SLC6A4 | |
| SCHEMBL21142126 | 0.80 | IDO1 (0.50) | IDO1FFAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12320190 | 0.80 | FFAR1 (0.52) | IDO1FFAR1CYP11B2PDPK1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368876-A1 | Derivatives of aminoindanes, their preparation and their application in therapeutics | SANOFI (FR) | 2011-09-28 | — | — | EP | disclosed |