Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 6/20 | 0.70 |
| ▸ | TRPC3 | Q13507 | 3/20 | 0.70 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.70 |
| ▸ | SLC9A3 | P48764 | 14/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411827 | 0.89 | TRPC6 (0.70) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL12320503 | 0.89 | TRPC6 (0.75) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL2409210 | 0.89 | TRPC6 (0.75) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL2415293 | 0.89 | TRPC6 (0.75) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL2407246 | 0.89 | TRPC6 (0.70) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL2412070 | 0.88 | TRPC6 (0.73) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL12292856 | 0.88 | TRPC6 (0.80) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL12320507 | 0.86 | TRPC6 (0.67) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL2411086 | 0.86 | TRPC6 (0.68) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL2410546 | 0.86 | TRPC6 (0.68) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368876-A1 | Derivatives of aminoindanes, their preparation and their application in therapeutics | SANOFI (FR) | 2011-09-28 | — | — | EP | disclosed |