Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.53 |
| ▸ | SKP1 | P63208 | 1/20 | 0.53 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.53 |
| ▸ | ME3 | Q16798 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | YAP1 | P46937 | 2/20 | 0.47 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665123 | 0.94 | ACACB (0.52) | CKS1BSKP1SKP2ME3KMT2A | |
| SCHEMBL27451694 | 0.92 | CKS1B (0.53) | CKS1BSKP1SKP2ME3KMT2A | |
| SCHEMBL32665202 | 0.90 | CKS1B (0.52) | CKS1BSKP1SKP2ME3KMT2A | |
| SCHEMBL20887738 | 0.89 | KMT2A (0.50) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL32665084 | 0.87 | MAPT (0.45) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL21564567 | 0.86 | CKS1B (0.60) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL30931783 | 0.86 | CKS1B (0.60) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL2881659 | 0.85 | CKS1B (0.55) | CKS1BSKP1SKP2ME3KMT2A | |
| SCHEMBL21564375 | 0.85 | CKS1B (0.56) | CKS1BSKP1SKP2KMT2AL3MBTL1 | |
| SCHEMBL17830852 | 0.85 | CKS1B (0.61) | CKS1BSKP1SKP2ME3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
| US-20110230467-A1 | 4,6-DIAMINONICOTINAMIDE COMPOUND | ASTELLAS PHARMA INC. (JP) | 2011-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230467-A1 | 4,6-DIAMINONICOTINAMIDE COMPOUND | JAK3, JAK2, JAK1 | CKS1B 2114/4885SKP1 2331/4885SKP2 917/4885 |
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | CKS1B 532/4885SKP1 3987/4885SKP2 1800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.