SCHEMBL17830852

SCHEMBL17830852

CC(C)(C)OC(=O)NC1CCN(c2ccccc2)CC1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CKS1B P61024 1/20 0.61
SKP1 P63208 1/20 0.61
SKP2 Q13309 1/20 0.61
GPR119 Q8TDV5 1/20 0.60
KCNA3 P22001 1/20 0.57
KDM1A O60341 1/20 0.55
MAOB P27338 1/20 0.55
KMT2A Q03164 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
DRD2 P14416 4/20 0.52
EPHX2 P34913 2/20 0.51
NAMPT P43490 1/20 0.51
PIM1 P11309 1/20 0.50
PIM3 Q86V86 1/20 0.50
PIM2 Q9P1W9 1/20 0.50
OPRM1 P35372 1/20 0.49
OPRD1 P41143 1/20 0.49
OPRK1 P41145 1/20 0.49
OGFRL1 Q5TC84 1/20 0.49
ME3 Q16798 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23500781 0.92 CKS1B (0.56) CKS1BSKP1SKP2GPR119KCNA3
SCHEMBL15222937 0.92 CKS1B (0.56) CKS1BSKP1SKP2GPR119KCNA3
SCHEMBL2881659 0.90 CKS1B (0.55) CKS1BSKP1SKP2GPR119KCNA3
SCHEMBL383106 0.88 USP2 (0.56) CKS1BSKP1SKP2GPR119KCNA3
SCHEMBL23841095 0.88 GPR119 (0.59) CKS1BSKP1SKP2GPR119KCNA3
SCHEMBL3130708 0.88 CKS1B (0.52) CKS1BSKP1SKP2GPR119KCNA3
SCHEMBL32665409 0.88 ME3 (0.54) CKS1BSKP1SKP2GPR119KCNA3
SCHEMBL3865823 0.87 KDM1A (0.52) CKS1BSKP1SKP2GPR119KCNA3
SCHEMBL1456142 0.86 CKS1B (0.54) CKS1BSKP1SKP2GPR119KCNA3
SCHEMBL5216885 0.86 CHRM4 (0.53) CKS1BSKP1SKP2GPR119KCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4662206-A1 GSPT1 DEGRADER COMPOUNDS Captor Therapeutics S.A. (PL) 2025-12-17 EP disclosed
WO-2024165577-A1 GSPT1 DEGRADER COMPOUNDS CAPTOR THERAPEUTICS S.A. (PL) 2024-08-15 WO disclosed
EP-3725787-B1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS REGENACY PHARMACEUTICALS INC (US) 2023-11-29 EP disclosed
US-20230348389-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS REGENACY PHARMACEUTICALS LLC (US) 2023-11-02 US disclosed
US-20230348389-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS REGENACY PHARMACEUTICALS LLC (US) 2023-11-02 US disclosed
US-11702389-B2 Piperidine derivatives as HDAC1/2 inhibitors REGENACY PHARMACEUTICALS, LLC (US) 2023-07-18 US disclosed
US-11702389-B2 Piperidine derivatives as HDAC1/2 inhibitors REGENACY PHARMACEUTICALS, LLC (US) 2023-07-18 US disclosed
US-20210179559-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS REGENACY PHARMACEUTICALS, LLC 2021-06-17 US disclosed
US-10968180-B2 Piperidine derivatives as HDAC1/2 inhibitors REGENACY PHARMACEUTICALS, LLC (US) 2021-04-06 US disclosed
EP-3292113-B1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS REGENACY PHARMACEUTICALS LLC (US) 2020-07-08 EP disclosed
US-10239837-B2 Piperidine derivatives as HDAC1/2 inhibitors REGENACY PHARMACEUTICALS, LLC (US) 2019-03-26 US disclosed
US-20180022702-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS ACETYLON PHARMACEUTICALS, INC. 2018-01-25 US disclosed
US-20180022702-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS ACETYLON PHARMACEUTICALS, INC. 2018-01-25 US disclosed
US-20170369441-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS REGENACY PHARMACEUTICALS, LLC 2017-12-28 US disclosed
US-20170340604-A1 THERAPEUTIC COMPOUNDS AND USES THEREOF GENENTECH, INC. (US) 2017-11-30 US disclosed
US-20170340604-A1 THERAPEUTIC COMPOUNDS AND USES THEREOF GENENTECH, INC. (US) 2017-11-30 US disclosed
US-9790180-B2 Piperidine derivatives as HDAC1/2 inhibitors REGENACY PHARMACEUTICALS, LLC (US) 2017-10-17 US disclosed
US-9790180-B2 Piperidine derivatives as HDAC1/2 inhibitors REGENACY PHARMACEUTICALS, LLC (US) 2017-10-17 US disclosed
US-20160168093-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS REGENACY PHARMACEUTICALS, LLC 2016-06-16 US disclosed
US-20160168093-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS REGENACY PHARMACEUTICALS, LLC 2016-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160168093-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS HDAC1, HDAC2, HDAC10 CKS1B 771/4885SKP1 1267/4885SKP2 103/4885
US-20170369441-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS HDAC1, HDAC2, HDAC10 CKS1B 771/4885SKP1 1267/4885SKP2 103/4885
US-20210179559-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS HDAC1, HDAC2, HDAC10 CKS1B 771/4885SKP1 1267/4885SKP2 103/4885
US-11702389-B2 Piperidine derivatives as HDAC1/2 inhibitors HDAC1, HDAC2, HDAC10 CKS1B 771/4885SKP1 1267/4885SKP2 103/4885
US-20230348389-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS HDAC1, HDAC2, HDAC10 CKS1B 771/4885SKP1 1267/4885SKP2 103/4885
US-10968180-B2 Piperidine derivatives as HDAC1/2 inhibitors HDAC1, HDAC2, HDAC10 CKS1B 771/4885SKP1 1267/4885SKP2 103/4885
US-10239837-B2 Piperidine derivatives as HDAC1/2 inhibitors HDAC1, HDAC2, HDAC10 CKS1B 771/4885SKP1 1267/4885SKP2 103/4885
US-20180022702-A1 PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS HDAC1, HDAC2, HDAC10 CKS1B 771/4885SKP1 1267/4885SKP2 103/4885
US-20170340604-A1 THERAPEUTIC COMPOUNDS AND USES THEREOF BRD4, BRDT, BRD3 CKS1B 239/4885SKP1 2240/4885SKP2 2256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.