Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.47 |
| ▸ | ITGAL | P20701 | 2/20 | 0.47 |
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12322755 | 0.88 | HRH3 (0.43) | HRH4HRH3ALDH1A1NFKB1CYP1A2 | |
| SCHEMBL13979576 | 0.83 | CYP3A4 (0.51) | HRH4HRH3ALDH1A1NFKB1CYP1A2 | |
| SCHEMBL15119370 | 0.83 | CYP3A4 (0.51) | HRH4HRH3ALDH1A1NFKB1CYP1A2 | |
| SCHEMBL1641647 | 0.83 | CYP3A4 (0.51) | HRH4HRH3ALDH1A1NFKB1CYP1A2 | |
| SCHEMBL29405299 | 0.82 | ITGB2 (0.56) | HRH4HRH3ALDH1A1NFKB1CYP1A2 | |
| SCHEMBL17697368 | 0.82 | CYP3A4 (0.54) | HRH4HRH3ALDH1A1NFKB1CYP1A2 | |
| SCHEMBL15080457 | 0.82 | REN (0.54) | HRH4HRH3ALDH1A1NFKB1CYP1A2 | |
| SCHEMBL18748750 | 0.81 | CYP3A4 (0.49) | HRH4HRH3ALDH1A1NFKB1CYP1A2 | |
| SCHEMBL12829313 | 0.79 | CYP3A4 (0.48) | HRH4HRH3ALDH1A1NFKB1CYP1A2 | |
| SCHEMBL13187470 | 0.78 | ITGB2 (0.49) | HRH4HRH3ALDH1A1NFKB1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119887-A1 | RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS | RXI PHARMACEUTICALS CORPORATION (US) | 2011-09-29 | — | — | WO | disclosed |