SCHEMBL12323976

SCHEMBL12323976

O=C(NCCCn1ccnc1)c1ccccc1O

nearest known ligand 0.76

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.69
KMT2A Q03164 4/20 0.69
HSD17B10 Q99714 3/20 0.68
SMN1; SMN2 Q16637 4/20 0.65
NPC1 O15118 1/20 0.64
ALDH1A1 P00352 2/20 0.63
HPGD P15428 1/20 0.63
TDP1 Q9NUW8 1/20 0.63
KDM4E B2RXH2 1/20 0.62
LMNA P02545 1/20 0.62
THRB P10828 1/20 0.62
TSHR P16473 1/20 0.61
TP53 P04637 2/20 0.60
MAPK1 P28482 2/20 0.60
POLB P06746 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10856486 0.88 MEN1 (0.70) MEN1KMT2AHSD17B10SMN1; SMN2NPC1
SCHEMBL14552522 0.88 MEN1 (0.69) MEN1KMT2AHSD17B10SMN1; SMN2NPC1
SCHEMBL10655218 0.87 MEN1 (0.69) MEN1KMT2AHSD17B10SMN1; SMN2NPC1
SCHEMBL14552329 0.86 SMN1; SMN2 (0.66) MEN1KMT2ASMN1; SMN2NPC1ALDH1A1
SCHEMBL14552489 0.85 KDM4E (0.70) MEN1KMT2AHSD17B10SMN1; SMN2NPC1
SCHEMBL11010135 0.85 MEN1 (0.69) MEN1KMT2AHSD17B10SMN1; SMN2NPC1
SCHEMBL14552392 0.85 MEN1 (0.66) MEN1KMT2AHSD17B10SMN1; SMN2NPC1
SCHEMBL14552420 0.84 MEN1 (0.83) MEN1KMT2AHSD17B10SMN1; SMN2NPC1
SCHEMBL10654653 0.84 MEN1 (0.64) MEN1KMT2AHSD17B10SMN1; SMN2NPC1
SCHEMBL14552404 0.83 MEN1 (0.64) MEN1KMT2AHSD17B10SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130203895-A1 CURING AGENTS FOR EPOXY RESINS DESIGNER MOLECULES, INC. (US) 2013-08-08 US disclosed
US-20130203895-A1 CURING AGENTS FOR EPOXY RESINS DESIGNER MOLECULES, INC. (US) 2013-08-08 US disclosed
US-20130012620-A1 CURING AGENTS FOR EPOXY RESINS DESIGNER MOLECULES, INC. (US) 2013-01-10 US disclosed
US-20130012620-A1 CURING AGENTS FOR EPOXY RESINS DESIGNER MOLECULES, INC. (US) 2013-01-10 US disclosed
WO-2011116050-A2 CURING AGENTS FOR EPOXY RESINS DESIGNER MOLECULES, INC. (US) 2011-09-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012620-A1 CURING AGENTS FOR EPOXY RESINS DOT1L, EHMT1, ASH1L MEN1 3864/4885KMT2A 271/4885HSD17B10 2620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.