Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24911011 | 1.00 | GBA1 (0.38) | GBA1EIF2AK4CNR1 | |
| SCHEMBL29323149 | 1.00 | GBA1 (0.38) | GBA1EIF2AK4CNR1 | |
| SCHEMBL16418013 | 0.81 | GBA1 (0.40) | GBA1 | |
| SCHEMBL12371254 | 0.81 | GBA1 (0.40) | GBA1 | |
| SCHEMBL16418011 | 0.81 | GBA1 (0.40) | GBA1 | |
| SCHEMBL15221487 | 0.81 | GBA1 (0.39) | GBA1EIF2AK4 | |
| SCHEMBL15132383 | 0.79 | GBA1 (0.34) | GBA1 | |
| SCHEMBL22360699 | 0.79 | GBA1 (0.34) | GBA1 | |
| SCHEMBL21039435 | 0.79 | GBA1 (0.34) | GBA1EIF2AK4 | |
| SCHEMBL29336568 | 0.78 | GBA1 (0.33) | GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601297-B9 | COMPOUNDS THAT INHIBIT MCL-1 PROTEIN | AMGEN INC (US) | 2023-05-24 | — | — | EP | disclosed |
| WO-2020168172-A1 | CONJUGATE COMPOUNDS FOR THE DEGRADATION OF RAF | ZAMBONI CHEM SOLUTIONS INC. (CA) | 2020-08-20 | — | — | WO | disclosed |
| WO-2011117381-A1 | B-RAF KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-09-29 | — | — | WO | disclosed |