Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 20/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 11/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14592358 | 0.87 | ITGB1 (0.74) | ITGA4ITGB1 | |
| SCHEMBL14592357 | 0.86 | ITGA4 (0.65) | ITGA4ITGB1 | |
| SCHEMBL2435276 | 0.81 | PTGER4 (0.40) | ITGA4ITGB1 | |
| SCHEMBL14592356 | 0.78 | SMN1; SMN2 (0.44) | ITGA4ITGB1 | |
| SCHEMBL12327471 | 0.77 | ITGA4 (0.59) | ITGA4ITGB1 | |
| SCHEMBL12328235 | 0.77 | ITGA4 (0.59) | ITGA4ITGB1 | |
| SCHEMBL14592353 | 0.74 | ITGB1 (0.79) | ITGA4ITGB1 | |
| SCHEMBL14592350 | 0.73 | ITGA4 (0.70) | ITGA4ITGB1 | |
| SCHEMBL12328224 | 0.73 | ITGA4 (0.56) | ITGA4ITGB1 | |
| SCHEMBL12327296 | 0.72 | ITGA4 (0.70) | ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346982-B1 | VLA-4 INHIBITORS | DAIICHI SEIYAKU CO (JP) | 2011-09-14 | — | — | EP | disclosed |