Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331403 | 0.88 | MAOB (0.53) | PPARGPPARAKMT2ACYP2C9NPC1 | |
| SCHEMBL11401778 | 0.87 | PPARG (0.58) | PPARGPPARAKMT2ACYP2C9CYP2C19 | |
| SCHEMBL593324 | 0.86 | AKR1C3 (0.59) | AKR1C3KMT2ANR4A2CYP2C9NR4A1 | |
| SCHEMBL2436356 | 0.85 | PPARA (0.50) | PPARGPPARAKMT2ANPC1POLB | |
| SCHEMBL2436622 | 0.84 | AKR1C3 (0.50) | AKR1C3PPARGPPARAKMT2ANR4A2 | |
| SCHEMBL12987433 | 0.83 | AKR1C3 (0.56) | AKR1C3PPARGKMT2ANR4A2CYP2C9 | |
| SCHEMBL27867052 | 0.83 | AKR1C3 (0.56) | AKR1C3KMT2ANR4A2CYP2C9NR4A1 | |
| SCHEMBL3845579 | 0.82 | PPARG (0.56) | PPARGPPARAKMT2ACYP2C9POLB | |
| SCHEMBL15445136 | 0.82 | PPARA (0.52) | PPARGPPARAKMT2ACYP2C9POLB | |
| SCHEMBL11399949 | 0.82 | PPARG (0.57) | PPARGPPARAFABP2SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |