Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2441559 | 0.85 | SMN1; SMN2 (0.47) | KMT2ANPC1RAB9APOLBMRGPRX4 | |
| SCHEMBL12327872 | 0.84 | AKR1C3 (0.56) | AKR1C3KMT2ANR4A2NPC1RAB9A | |
| SCHEMBL593324 | 0.84 | AKR1C3 (0.59) | AKR1C3KMT2ANR4A2NPC1RAB9A | |
| SCHEMBL1549954 | 0.82 | PPARA (0.60) | AKR1C3KMT2ANR4A2NPC1RAB9A | |
| SCHEMBL18804484 | 0.82 | PPARA (0.46) | KMT2APOLBCYP2C9KDM4EPPARG | |
| SCHEMBL977500 | 0.81 | CA1 (0.48) | KMT2ANR4A2CYP2C9RXRARXRB | |
| SCHEMBL14943944 | 0.80 | CYP3A4 (0.44) | POLBPPARGPPARA | |
| SCHEMBL30609812 | 0.80 | CYP1A2 (0.41) | KMT2ACYP2C9MRGPRX4KDM4EPPARG | |
| SCHEMBL4576129 | 0.80 | CYP1A2 (0.41) | KMT2ACYP2C9MRGPRX4KDM4EPPARG | |
| SCHEMBL1550516 | 0.78 | PPARA (0.49) | AKR1C3RXRAPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |