Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171450 | 0.91 | DAO (0.51) | DAOKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL1233498 | 0.90 | DAO (0.52) | DAOKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL1170986 | 0.88 | DAO (0.56) | DAOKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL1171173 | 0.88 | DAO (0.63) | DAOKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL1171059 | 0.86 | DAO (0.54) | DAOKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL1171028 | 0.85 | DAO (0.48) | DAOKDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL1170889 | 0.85 | GPR84 (0.53) | DAOKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL1171408 | 0.84 | GPR84 (0.55) | DAOKDM4EALDH1A1RAB9AHSD17B10 | |
| SCHEMBL12864156 | 0.84 | GPR84 (0.55) | DAOKDM4EALDH1A1RAB9AHSD17B10 | |
| SCHEMBL1171015 | 0.83 | DAO (0.59) | DAOKDM4EALDH1A1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011017634-A2 | PRODRUGS OF FUSED HETEROCYCLIC INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACORE INC. (US) | 2011-02-10 | — | — | WO | disclosed |