Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 20/20 | 0.72 |
| ▸ | ITGB1 | P05556 | 17/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14592341 | 0.93 | ITGB1 (0.84) | ITGA4ITGB1 | |
| SCHEMBL14592342 | 0.84 | ITGB1 (1.00) | ITGA4ITGB1 | |
| SCHEMBL12327296 | 0.77 | ITGA4 (0.70) | ITGA4ITGB1 | |
| SCHEMBL14592686 | 0.76 | ITGA4 (1.00) | ITGA4ITGB1 | |
| SCHEMBL14592649 | 0.76 | ITGB1 (0.85) | ITGA4ITGB1 | |
| SCHEMBL2437969 | 0.75 | ITGB1 (0.46) | ITGA4ITGB1 | |
| SCHEMBL14592709 | 0.75 | ITGA4 (0.88) | ITGA4ITGB1 | |
| SCHEMBL14592319 | 0.75 | ITGA4 (0.84) | ITGA4ITGB1 | |
| SCHEMBL14592347 | 0.75 | ITGB1 (1.00) | ITGA4ITGB1 | |
| SCHEMBL14592318 | 0.75 | ITGA4 (0.75) | ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1346982-B1 | VLA-4 INHIBITORS | DAIICHI SEIYAKU CO (JP) | 2011-09-14 | — | — | EP | disclosed |