Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.40 |
| ▸ | ACACA | Q13085 | 11/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12329323 | 0.87 | ACACB (0.47) | ACACBACACAPDE7ASLC6A3SLC6A4 | |
| SCHEMBL15489232 | 0.85 | ACACB (0.43) | ACACBACACAPDE7ACES1KMT2A | |
| SCHEMBL732782 | 0.83 | ACACB (0.52) | ACACBACACA | |
| SCHEMBL12214972 | 0.82 | ACACB (0.53) | ACACBACACACES1 | |
| SCHEMBL12329322 | 0.81 | ACACB (0.47) | ACACBACACACES1SLC6A3SLC6A4 | |
| SCHEMBL16556748 | 0.80 | ACACB (0.49) | ACACBACACACES1 | |
| SCHEMBL13940440 | 0.79 | ACACB (0.43) | ACACBACACAPDE7ACES1KMT2A | |
| SCHEMBL15489227 | 0.78 | ACACB (0.46) | ACACBACACAPDE7ACES1KMT2A | |
| SCHEMBL15472956 | 0.78 | ACACB (0.44) | ACACBACACAPDE7ACES1 | |
| SCHEMBL12461726 | 0.78 | ACACB (0.64) | ACACBACACACES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761490-B1 | 3'-ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2011-09-07 | — | — | EP | disclosed |