Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.52 |
| ▸ | ACACA | Q13085 | 11/20 | 0.52 |
| ▸ | PDE7B | Q9NP56 | 6/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL732773 | 0.95 | ACACB (0.54) | ACACBACACAPDE7B | |
| SCHEMBL734193 | 0.89 | ACACB (0.49) | ACACBACACAPDE7BGAA | |
| SCHEMBL11990113 | 0.88 | ACACB (0.65) | ACACBACACAPDE7BTP53GAA | |
| SCHEMBL14537958 | 0.86 | ACACB (0.46) | ACACBACACA | |
| SCHEMBL12329323 | 0.86 | ACACB (0.47) | ACACBACACAPDE7B | |
| SCHEMBL732322 | 0.85 | ACACB (0.41) | ACACBACACAPDE7BTP53 | |
| SCHEMBL12329324 | 0.83 | ACACB (0.40) | ACACBACACA | |
| SCHEMBL733881 | 0.82 | ACACB (0.68) | ACACBACACAPDE7B | |
| SCHEMBL12214972 | 0.81 | ACACB (0.53) | ACACBACACA | |
| SCHEMBL2351074 | 0.81 | ACACB (0.80) | ACACBACACATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943218-B1 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | BAYER IP GMBH (DE) | 2015-05-06 | — | — | EP | disclosed |
| US-8138119-B2 | Alkoxyalkyl spirocyclic tetramic acids and tetronic acids | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-8138119-B2 | Alkoxyalkyl spirocyclic tetramic acids and tetronic acids | BAYER CROPSCIENCE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20090215624-A1 | Alkoxyalkyl Spirocyclic Tetramic Acids and Tetronic Acids | BAYER CROPSCIENCE AG (DE) | 2009-08-27 | — | — | US | disclosed |
| US-20090215624-A1 | Alkoxyalkyl Spirocyclic Tetramic Acids and Tetronic Acids | BAYER CROPSCIENCE AG (DE) | 2009-08-27 | — | — | US | disclosed |
| WO-2007048545-A2 | ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS | BAYER CROPSCIENCE AG (DE) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215624-A1 | Alkoxyalkyl Spirocyclic Tetramic Acids and Tetronic Acids | DDT, TBCD, TBCA | ACACB 1097/4885ACACA 896/4885PDE7B 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.