Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | PYGL | P06737 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14653926 | 0.84 | KDM4E (0.64) | KDM4EHSD17B10PYGLHRH4HRH3 | |
| SCHEMBL16492505 | 0.83 | HDAC3 (0.65) | KDM4EHSD17B10PYGLITGB3ITGA2B | |
| SCHEMBL2444395 | 0.81 | HRH4 (0.57) | KDM4EPYGLHRH4HRH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL20267092 | 0.80 | KDM4E (0.82) | KDM4EHSD17B10ALDH1A1DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL2445525 | 0.80 | HRH4 (0.56) | KDM4EPYGLHRH4HRH3ALDH1A1 | |
| SCHEMBL5677265 | 0.77 | ITGB3 (0.54) | KDM4EHSD17B10PYGLITGB3ITGA2B | |
| SCHEMBL5889522 | 0.76 | KDM4E (0.53) | KDM4EHSD17B10PYGLITGB3ITGA2B | |
| SCHEMBL5889464 | 0.76 | KDM4E (0.50) | KDM4EHSD17B10PYGLITGB3ITGA2B | |
| SCHEMBL12330264 | 0.76 | HRH4 (0.44) | KDM4EHSD17B10HRH4HRH3HDAC3 | |
| SCHEMBL12086506 | 0.76 | HRH4 (0.55) | KDM4EHSD17B10HRH4HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2363399-A1 | Labelled analogues of halobenzamides as radiopharmaceuticals | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-09-07 | — | — | EP | disclosed |