SCHEMBL1233253

SCHEMBL1233253

COC(=O)/C=C/c1ccc(N)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.70
CA2 P00918 2/20 0.70
CA12 O43570 1/20 0.70
TYR P14679 1/20 0.70
CA7 P43166 1/20 0.70
CA9 Q16790 1/20 0.70
CA14 Q9ULX7 1/20 0.70
PTPN1 P18031 1/20 0.60
TTR P02766 1/20 0.59
APP P05067 1/20 0.59
EPHX2 P34913 1/20 0.58
KDM4E B2RXH2 3/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 3/20 0.53
HTT P42858 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
JAK2 O60674 1/20 0.53
GAA P10253 1/20 0.53
FDPS P14324 1/20 0.50
MEN1 O00255 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1233254 1.00 CA1 (0.70) CA1CA2CA12TYRCA7
Hydrochloric Acid SCHEMBL7439394 0.98 CA1 (0.68) CA1CA2CA12TYRCA7
Hydrochloric Acid SCHEMBL3552479 0.98 CA1 (0.68) CA1CA2CA12TYRCA7
SCHEMBL17457052 0.92 CA1 (0.60) CA1CA2CA12TYRCA7
SCHEMBL17457050 0.92 CA1 (0.60) CA1CA2CA12TYRCA7
SCHEMBL28852448 0.92 CA1 (0.60) CA1CA2CA12TYRCA7
SCHEMBL71224 0.90 CA12 (0.84) CA1CA2CA12TYRCA7
SCHEMBL5057418 0.90 CA12 (0.84) CA1CA2CA12TYRCA7
Hydrochloric Acid SCHEMBL27534488 0.87 CA12 (0.55) CA1CA2CA12TYRCA7
SCHEMBL18410060 0.85 MAPT (0.71) CA1CA2CA12TYRCA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118724825-A Mer/HDAC double-target inhibitor and application thereof in preparation of antitumor drugs 河北科技大学 2024-10-01 CN claimed
CN-101774918-A Preparation method of cinnamate derivates UNIV HUAQIAO 2010-07-14 CN claimed
EP-0713859-B1 Cinnamic acid derivatives, photocrosslinkable cinnamic acid-polymer derivative and crosslinked cinnamic acid polymer derivatives SEIKAGAKU KOGYO CO LTD (JP) 2000-08-30 EP claimed
CN-122095297-A Composition for forming cured film, alignment material, and phase difference material 2026-05-26 CN disclosed
EP-4719602-A1 ANTI-HIV COMPOUNDS GILEAD SCIENCES, INC. (US) 2026-04-08 EP disclosed
WO-2025088969-A1 COMPOSITION FOR FORMING CURED FILM, CURED FILM, ALIGNMENT MATERIAL, AND RETARDATION MATERIAL 日産化学株式会社 2025-05-01 WO disclosed
US-20250051375-A1 ANTI-HIV COMPOUNDS GILEAD SCIENCES, INC. 2025-02-13 US disclosed
WO-2025023309-A1 COMPOSITION FOR FORMING CURED FILM, ALIGNMENT MATERIAL, AND PHASE-DIFFERENCE MATERIAL 日産化学株式会社 2025-01-30 WO disclosed
WO-2025011632-A1 HYDROXIMIC ACID COMPOUNDS CONTAINING TETRAHYDROBENZO[4,5]FURANO[2,3-C]PYRIDINE, PREPARATION METHOD THEREFOR, AND USES THEREOF 浙江大学 2025-01-16 WO disclosed
WO-2024249517-A1 ANTI-HIV COMPOUNDS GILEAD SCIENCES, INC. (US) 2024-12-05 WO disclosed
CN-113874470-B Composition for forming cured film, alignment member, and phase difference member 日产化学株式会社 2024-11-19 CN disclosed
EP-0642508-A1 TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1995-03-15 EP disclosed
US-5360819-A Nonradioactive labels which provide a ketone signal, vapor phase analysis NORTHEASTERN UNIVERSITY (US) 1994-11-01 US disclosed
WO-1993008188-A1 TRICYCLIC QUINOXALINEDIONES AS GLUTAMATE RECEPTOR ANTAGONISTS SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1993-04-29 WO disclosed
US-5096919-A Pyrrolylphenyl-substituted hydroxamic acid derivatives CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0378991-A1 Certain pyrrolylphenyl-substituted hydroxamic acid derivatives CIBA-GEIGY AG (CH) 1990-07-25 EP disclosed
US-4388459-A HYPOLIPIDEMIC, ANTIATHEROSCLEROTIC AMERICAN CYANAMID COMPANY (US) 1983-06-14 US disclosed
US-4379819-A OIL SOLUBLE MONOAZO DYE CIBA-GEIGY AG (CH) 1983-04-12 US disclosed
US-4259352-A 4-[Cycloalkyl- or cycloalkenyl-amino(cycloalkyl- or cycloalkenyl-alkenyl)amino]phenyl compounds, useful as hypolipidemic and antiatherosclerotic agents AMERICAN CYANAMID COMPANY (US) 1981-03-31 US disclosed
US-4094636-A DIAZOTIZATION HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250051375-A1 ANTI-HIV COMPOUNDS CCR5, CD4, NFATC1 CA1 4857/4885CA2 4208/4885CA12 4488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.