Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24390060 | 0.84 | P2RX4 (0.35) | MAPTSMN1; SMN2NPSR1KMT2AHTT | |
| SCHEMBL2453063 | 0.84 | KMT2A (0.37) | MAPTSMN1; SMN2NPSR1KMT2AHTT | |
| SCHEMBL2453082 | 0.83 | AHR (0.37) | MAPTSMN1; SMN2NPSR1KMT2AHTT | |
| SCHEMBL24428116 | 0.82 | P2RX4 (0.39) | MAPTSMN1; SMN2NPSR1P2RX4 | |
| SCHEMBL16596831 | 0.78 | LPL (0.35) | MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL12723354 | 0.78 | MAPT (0.37) | MAPTSMN1; SMN2NPSR1KMT2AHTT | |
| SCHEMBL15434786 | 0.78 | KMT2A (0.36) | MAPTSMN1; SMN2NPSR1KMT2AHTT | |
| SCHEMBL9886660 | 0.76 | MAPT (0.34) | MAPTSMN1; SMN2NPSR1KMT2AHTT | |
| SCHEMBL9886636 | 0.76 | MAPT (0.34) | MAPTSMN1; SMN2NPSR1KMT2AHTT | |
| SCHEMBL9886694 | 0.75 | MAPT (0.33) | MAPTSMN1; SMN2NPSR1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011107186-A2 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-09-09 | — | — | WO | disclosed |