Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21889079 | 0.96 | KDM4E (0.44) | KDM4EL3MBTL1ATMALDH1A1HDAC4 | |
| SCHEMBL14296782 | 0.93 | KDM4E (0.40) | KDM4EL3MBTL1ATMALDH1A1MAPK8 | |
| SCHEMBL21888241 | 0.92 | KDM4E (0.45) | KDM4EL3MBTL1ATMALDH1A1HDAC4 | |
| SCHEMBL21889078 | 0.92 | KDM4E (0.42) | KDM4EL3MBTL1ATMALDH1A1HDAC4 | |
| SCHEMBL20383383 | 0.91 | KDM4E (0.36) | KDM4EL3MBTL1ATM | |
| SCHEMBL13143230 | 0.90 | L3MBTL1 (0.50) | KDM4EL3MBTL1ATMALDH1A1HDAC4 | |
| SCHEMBL18355542 | 0.89 | KDM4E (0.46) | KDM4EL3MBTL1ATMALDH1A1MAPK8 | |
| SCHEMBL3086844 | 0.89 | L3MBTL1 (0.53) | KDM4EL3MBTL1ATMALDH1A1HDAC4 | |
| SCHEMBL21888172 | 0.87 | KDM4E (0.40) | KDM4EL3MBTL1ATMHDAC4 | |
| SCHEMBL10309960 | 0.87 | KDM4E (0.40) | KDM4EL3MBTL1ATMHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11264575-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2022-03-01 | — | — | US | disclosed |
| US-10008673-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2018-06-26 | — | — | US | disclosed |
| US-10008673-B2 | Compounds for electronic devices | MERCK PATENT GMBH (DE) | 2018-06-26 | — | — | US | disclosed |
| US-20170155062-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-06-01 | — | — | US | disclosed |
| US-20170155062-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-06-01 | — | — | US | disclosed |
| US-20170155062-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-06-01 | — | — | US | disclosed |
| US-20120319052-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| US-20120319052-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| US-20120319052-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| WO-2011107186-A2 | COMPOUNDS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-09-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11264575-B2 | Compounds for electronic devices | CYP2C19, CYP2C18, CYP1B1 | KDM4E 3090/4885L3MBTL1 4058/4885ATM 4528/4885 |
| US-20170155062-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP1B1, CYP1A1, CYP2E1 | KDM4E 2681/4885L3MBTL1 3745/4885ATM 4337/4885 |
| US-10008673-B2 | Compounds for electronic devices | CYP1B1, CYP1A1, CYP2E1 | KDM4E 2681/4885L3MBTL1 3745/4885ATM 4337/4885 |
| US-20120319052-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | CYP1B1, CYP1A1, CYP2E1 | KDM4E 2681/4885L3MBTL1 3745/4885ATM 4337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.