Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.67 |
| ▸ | APAF1 | O14727 | 12/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | HTT | P42858 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | GAA | P10253 | 5/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.67 |
| ▸ | NSD2 | O96028 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | POLB | P06746 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | MITF | O75030 | 2/20 | 0.66 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.56 |
| ▸ | CDC25A | P30304 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462511 | 0.88 | MAPT (0.67) | MAPTAPAF1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2462507 | 0.87 | APAF1 (0.69) | MAPTAPAF1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL16297270 | 0.84 | MAPT (0.71) | MAPTAPAF1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL16297028 | 0.82 | MAPT (0.73) | MAPTAPAF1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL7247303 | 0.81 | MAPT (0.97) | MAPTAPAF1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL16297241 | 0.81 | APAF1 (0.71) | MAPTAPAF1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2462638 | 0.81 | MAPT (0.71) | MAPTAPAF1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2464285 | 0.81 | APAF1 (0.72) | MAPTAPAF1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL16297187 | 0.80 | APAF1 (1.00) | MAPTAPAF1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2465538 | 0.80 | MAPT (1.00) | MAPTAPAF1ALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011113060-A2 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | TRANA DISCOVERY, INC. (US) | 2011-09-15 | — | — | WO | disclosed |