Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.67 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334215 | 0.90 | GPR119 (0.67) | GPR119ACACB | |
| SCHEMBL2331529 | 0.87 | GPR119 (0.69) | GPR119ACACBMCHR1 | |
| SCHEMBL2334267 | 0.87 | GPR119 (0.79) | GPR119ACACB | |
| SCHEMBL2336792 | 0.87 | GPR119 (0.82) | GPR119 | |
| SCHEMBL2334867 | 0.84 | GPR119 (0.75) | GPR119ACACBMCHR1 | |
| SCHEMBL2333344 | 0.83 | GPR119 (0.76) | GPR119ACACBMCHR1 | |
| SCHEMBL2333159 | 0.83 | GPR119 (0.80) | GPR119ACACBMCHR1 | |
| SCHEMBL2339476 | 0.82 | GPR119 (0.82) | GPR119 | |
| SCHEMBL11955169 | 0.82 | GPR119 (0.70) | GPR119ACACB | |
| SCHEMBL12447082 | 0.82 | GPR119 (0.73) | GPR119ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170864-B1 | PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2011-09-14 | — | — | EP | disclosed |