Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725914 | 0.97 | ALDH1A1 (0.52) | ALDH1A1DNM1MEN1KMT2ATSHR | |
| SCHEMBL18822227 | 0.97 | ALDH1A1 (0.52) | ALDH1A1DNM1MEN1KMT2ATSHR | |
| SCHEMBL24883881 | 0.97 | ALDH1A1 (0.52) | ALDH1A1DNM1MEN1KMT2ATSHR | |
| SCHEMBL11754625 | 0.95 | ALDH1A1 (0.55) | ALDH1A1DNM1MEN1KMT2ATSHR | |
| SCHEMBL11522031 | 0.95 | ALDH1A1 (0.55) | ALDH1A1DNM1MEN1KMT2ATSHR | |
| Hydrochloric Acid SCHEMBL27922519 | 0.95 | ALDH1A1 (0.50) | ALDH1A1DNM1MEN1KMT2ATSHR | |
| Iodide SCHEMBL29117504 | 0.95 | ALDH1A1 (0.50) | ALDH1A1DNM1MEN1KMT2ATSHR | |
| SCHEMBL28236086 | 0.95 | ALDH1A1 (0.55) | ALDH1A1DNM1MEN1KMT2ATSHR | |
| SCHEMBL1008995 | 0.95 | ALDH1A1 (0.55) | ALDH1A1DNM1MEN1KMT2ATSHR | |
| SCHEMBL8977215 | 0.95 | ALDH1A1 (0.55) | ALDH1A1DNM1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017151-B2 | Amphiphilic polymer-protein conjugates and methods of use thereof | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA BY AND BEHALF OF THE UNIVERSITY OF NEBRASKA MEDICAL CENTER (US) | 2011-09-13 | — | — | US | disclosed |