Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.71 |
| ▸ | APAF1 | O14727 | 11/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | POLB | P06746 | 5/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | CASP3 | P42574 | 1/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | CDC25A | P30304 | 2/20 | 0.61 |
| ▸ | CDC25B | P30305 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | MITF | O75030 | 3/20 | 0.48 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12334430 | 0.90 | MAPT (0.73) | MAPTAPAF1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL14777433 | 0.87 | MAPT (0.79) | MAPTAPAF1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL16297010 | 0.79 | MAPT (0.80) | MAPTAPAF1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL12333609 | 0.77 | CDC25A (0.98) | MAPTAPAF1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL12010991 | 0.76 | MAPT (0.71) | MAPTAPAF1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL2525803 | 0.72 | MAPT (0.68) | MAPTAPAF1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL14777698 | 0.72 | MAPT (0.67) | MAPTAPAF1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL2467093 | 0.72 | APAF1 (0.80) | MAPTAPAF1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL16296982 | 0.72 | MAPT (0.67) | MAPTAPAF1ALDH1A1POLBL3MBTL1 | |
| SCHEMBL19625600 | 0.70 | MAPT (0.69) | MAPTAPAF1ALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011113060-A2 | ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF | TRANA DISCOVERY, INC. (US) | 2011-09-15 | — | — | WO | disclosed |