Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL662955 | 0.92 | FFAR1 (0.44) | PABPC1CYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4239977 | 0.84 | PABPC1 (0.46) | PABPC1CYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31136401 | 0.78 | IDO1 (0.45) | PABPC1CYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5271971 | 0.76 | KDM4E (0.51) | SCN9AHTTKMT2AKDM4ETDP1 | |
| SCHEMBL24258289 | 0.74 | HRH3 (0.62) | HTTKMT2AMEN1KDM4EHRH3 | |
| SCHEMBL23545645 | 0.74 | IDO1 (0.47) | PABPC1TSHRKMT2AMEN1KDM4E | |
| SCHEMBL30471887 | 0.74 | CYP1A2 (0.43) | CYP2D6CYP1A2CYP2C9CYP2C19SCN9A | |
| SCHEMBL23545638 | 0.74 | CYP1A2 (0.43) | CYP2D6CYP1A2CYP2C9CYP2C19SCN9A | |
| SCHEMBL4244332 | 0.73 | CARM1 (0.63) | KMT2AMEN1KDM4EGAAHRH3 | |
| SCHEMBL19650831 | 0.73 | PABPC1 (0.50) | PABPC1CYP2D6CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109441-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYREXIS, INC. (US) | 2011-09-09 | — | — | WO | disclosed |