SCHEMBL12335752

SCHEMBL12335752

Cc1cc(S)c(-c2oc(C)cc2S)o1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.41
CA1 P00915 3/20 0.36
CA9 Q16790 3/20 0.36
TDP1 Q9NUW8 1/20 0.35
MEN1 O00255 1/20 0.33
GLA P06280 1/20 0.33
CYP3A4 P08684 1/20 0.33
KMT2A Q03164 1/20 0.33
CA12 O43570 1/20 0.32
CA3 P07451 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL755488 0.75
SCHEMBL5158898 0.67
SCHEMBL11928939 0.63 NQO1 (0.48) NQO1CA1CA9TDP1MEN1
SCHEMBL5039621 0.62 NQO1 (0.47) NQO1CA1CA9TDP1MEN1
SCHEMBL7663185 0.61
SCHEMBL9586 0.58
SCHEMBL15918971 0.58 CA1 (0.43) NQO1CA1CA9TDP1MEN1
SCHEMBL182910 0.58
SCHEMBL3185677 0.58 ALDH1A1 (0.34) CA1TDP1CYP3A4
SCHEMBL7682213 0.58 CYP3A4 (0.37) CA1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011119446-A1 PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME POLYERA CORPORATION (US) 2011-09-29 WO disclosed