Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.61 |
| ▸ | COMT | P21964 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 3/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6240439 | 0.77 | — | — | |
| SCHEMBL20439962 | 0.72 | — | — | |
| SCHEMBL12537263 | 0.69 | COMT (0.52) | ALOX5COMTLMNAHTTNPC1 | |
| SCHEMBL18400504 | 0.69 | ALOX5 (0.39) | ALOX5 | |
| SCHEMBL12890180 | 0.67 | — | — | |
| SCHEMBL16284914 | 0.65 | ALOX5 (0.36) | ALOX5COMTLMNAHTTNPC1 | |
| SCHEMBL20439926 | 0.63 | — | — | |
| SCHEMBL15001035 | 0.63 | CCNE1 (0.41) | ALOX5COMTLMNAHTTNPC1 | |
| SCHEMBL12973032 | 0.61 | CDK4 (0.45) | ALOX5LMNAHTTCDK4 | |
| SCHEMBL13470368 | 0.61 | CDK4 (0.45) | ALOX5LMNAHTTCDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119446-A1 | PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME | POLYERA CORPORATION (US) | 2011-09-29 | — | — | WO | disclosed |