SCHEMBL123396

SCHEMBL123396

CC(=O)CC(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL8462750 0.91 ALDH1A1 (0.33)
SCHEMBL8461195 0.84 KDM4E (0.30)
Thiophene SCHEMBL27624561 0.81
SCHEMBL8534509 0.80 ALDH1A1 (0.39)
SCHEMBL18265160 0.79
SCHEMBL4206545 0.79 KDM4E (0.44)
SCHEMBL18559850 0.79
SCHEMBL15113111 0.78
SCHEMBL11289793 0.78
SCHEMBL31412009 0.77 KDM4E (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 598 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118420855-A Polyelectrolyte material with high alkali resistance and high conductivity 广东鸣洋科技有限公司 2024-08-02 CN claimed
CN-117427369-A Method for separating mixture of HFO-1234ze (Z) and HFC-245fa 陕西中蓝化工科技新材料有限公司 2024-01-23 CN claimed
JP-4705109-B2 2011-06-22 JP claimed
EP-2176258-A1 PIPERIDINE DERIVATIVES USEFUL AS OREXIN RECEPTOR ANTAGONISTS Glaxo Group Limited (GB) 2010-04-21 EP claimed
EP-1814837-B1 A METHOD FOR PRODUCING 4,4,4-TRIFLUOROBUTANE-2-ONE CENTRAL GLASS CO LTD (JP) 2010-02-24 EP claimed
US-7615668-B2 Method for producing 4,4,4-trifluorobutane-2-one CENTRAL GLASS CO., LTD. (JP) 2009-11-10 US claimed
US-20090227821-A1 Method for producing 4,4,4- Trifluorobutane-2-One CENTRAL GLASS CO., LTD. (JP) 2009-09-10 US claimed
WO-2009003993-A1 PIPERIDINE DERIVATIVES USEFUL AS OREXIN RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2009-01-08 WO claimed
EP-1814837-A4 A METHOD FOR PRODUCING 4,4,4-TRIFLUOROBUTANE-2-ONE CENTRAL GLASS CO LTD (JP) 2007-12-26 EP claimed
EP-1814837-A1 A METHOD FOR PRODUCING 4,4,4-TRIFLUOROBUTANE-2-ONE Central Glass Co., Ltd. (JP) 2007-08-08 EP claimed
WO-2006043946-A1 A METHOD FOR PRODUCING 4,4,4-TRIFLUOROBUTANE-2-ONE CENTRAL GLASS CO., LTD. (JP) 2006-04-27 WO claimed
CN-1455663-A Novel aerosol formulation containing polar fluorinated molecule ASTRAZENECA AB (SE) 2003-11-12 CN claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
US-6346402-B1 ACTS ON OPTICALLY ACTIVE (S)-ALPHA-PHENETHYLAMINE AND PYRUVIC ACID TO FORM ACETOPHENONE AND ALANINE; FOR PRODUCING CHEMICAL INTERMEDIATES OF DRUGS AND AGRICULTURAL CHEMICALS KANEKA CORPORATION (JP) 2002-02-12 US claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed
EP-1045025-A1 (S)-alpha-PHENETHYLAMINE : PYRUVATE TRANSAMINASE KANEKA CORPORATION (JP) 2000-10-18 EP claimed
JP-7017944-A None JP disclosed
US-4479007-A Chroman-4-ones and process for preparing same BAYER AKTIENGESELLSCHAFT (DE) 1984-10-23 US disclosed
US-4415741-A REACTING O-HYDROXYACETOPHENONE AND CYCLOPENTANONE BAYER AKTIENGESELLSCHAFT (DE) 1983-11-15 US disclosed