Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.37 |
| ▸ | NPY4R | P50391 | 9/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.35 |
| ▸ | NPY1R | P25929 | 6/20 | 0.35 |
| ▸ | NPY2R | P49146 | 3/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10303447 | 0.91 | NPY4R (0.40) | NPY4RNPY5RNPY1RNPY2RMMP1 | |
| SCHEMBL10303439 | 0.83 | MMP1 (0.42) | NPY4RNPY5RNPY1RNPY2RMMP1 | |
| SCHEMBL12340429 | 0.83 | IL23R (0.39) | IL23RNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL10303451 | 0.82 | NPY4R (0.42) | NPY4RNPY5RNPY1RNPY2RMMP1 | |
| SCHEMBL12340423 | 0.81 | NPY4R (0.48) | IL23RNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL13248708 | 0.81 | NPY4R (0.55) | IL23RNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL12340421 | 0.81 | NPY4R (0.48) | IL23RNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL12340435 | 0.81 | NPY4R (0.55) | IL23RNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL12340422 | 0.81 | NPY4R (0.47) | IL23RNPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL10303436 | 0.80 | NPY4R (0.43) | NPY4RNPY5RNPY1RNPY2RMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268784-B2 | Neuropeptide-2 receptor (Y-2R) agonists and uses thereof | HOFFMANN-LA ROCHE INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-8268784-B2 | Neuropeptide-2 receptor (Y-2R) agonists and uses thereof | HOFFMANN-LA ROCHE INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20100137223-A1 | NEUROPEPTIDE-2 RECEPTOR (Y-2R) AGONISTS AND USES THEREOF | CONDE-KNAPE KARIN | 2010-06-03 | — | — | US | disclosed |
| US-20100137223-A1 | NEUROPEPTIDE-2 RECEPTOR (Y-2R) AGONISTS AND USES THEREOF | CONDE-KNAPE KARIN | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137223-A1 | NEUROPEPTIDE-2 RECEPTOR (Y-2R) AGONISTS AND USES THEREOF | NPY2R, NPY1R, NPY5R | IL23R 428/4885NPY4R 4/4885NPY5R 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.