Dymanthine

Dymanthine

SCHEMBL1234152

CC(=O)O.CCCCCCCCCCCCCCCCCCN(C)C

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Dymanthine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 known ✓ P03372 1/20 0.46
DNM1 Q05193 6/20 0.71
TSHR P16473 5/20 0.52
ALDH1A1 P00352 3/20 0.52
GPR84 Q9NQS5 7/20 0.46
PPARG P37231 7/20 0.46
PPARD Q03181 7/20 0.46
PPARA Q07869 7/20 0.46
HDAC11 Q96DB2 5/20 0.46
PTPN1 P18031 3/20 0.46
TLR2 O60603 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
FABP4 P15090 2/20 0.46
SLC22A6 Q4U2R8 1/20 0.46
SLC22A8 Q8TCC7 1/20 0.46
MEN1 O00255 1/20 0.46
ALOX15 P16050 1/20 0.46
PDE4A P27815 1/20 0.46
KMT2A Q03164 1/20 0.46
PDE3A Q14432 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL3139389 1.00 DNM1 (0.71) DNM1TSHRALDH1A1GPR84PPARG
Acetic Acid SCHEMBL10938689 1.00 DNM1 (0.71) DNM1TSHRALDH1A1GPR84PPARG
Acetic Acid SCHEMBL31440217 1.00 DNM1 (0.71) DNM1TSHRALDH1A1GPR84PPARG
Acetic Acid SCHEMBL30060683 1.00 DNM1 (0.71) DNM1TSHRALDH1A1GPR84PPARG
Acetic Acid SCHEMBL3915385 1.00 DNM1 (0.71) DNM1TSHRALDH1A1GPR84PPARG
Acetic Acid SCHEMBL5568676 1.00 DNM1 (0.71) DNM1TSHRALDH1A1GPR84PPARG
Acetic Acid SCHEMBL11028728 1.00 DNM1 (0.71) DNM1TSHRALDH1A1GPR84PPARG
Acetic Acid SCHEMBL339432 1.00 DNM1 (0.71) DNM1TSHRALDH1A1GPR84PPARG
Acetic Acid SCHEMBL829333 1.00 DNM1 (0.71) DNM1TSHRALDH1A1GPR84PPARG
Acetic Acid SCHEMBL1427590 1.00 DNM1 (0.71) DNM1TSHRALDH1A1GPR84PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326702-B1 AMINE SALTS AS STABILIZERS FOR THE OIL AND WATER REPELLENT FINISHING OF FIBRE MATERIALS Pfersee Chemie GmbH (DE) 1993-06-02 EP claimed
EP-0326702-A2 Amine salts as stabilizers for the oil and water repellent finishing of fibre materials Pfersee Chemie GmbH (DE) 1989-08-09 EP claimed
WO-2025058033-A1 PERFUME DELIVERY PARTICLES 花王株式会社 2025-03-20 WO disclosed
WO-2024095652-A1 NON-FLUORINE WATER-REPELLENT COMPOSITION AND METHOD FOR PRODUCING WATER-REPELLENT FIBER PRODUCT 日華化学株式会社 2024-05-10 WO disclosed
CN-115485431-B Treatment agent for synthetic fibers, and method for treating synthetic fibers 竹本油脂株式会社 2023-09-26 CN disclosed
EP-3460021-B1 WATER REPELLENT AND PRODUCTION PROCESS THEREFOR MEISEI CHEMICAL WORKS LTD (JP) 2023-06-28 EP disclosed
CN-115485431-A Treating agent for synthetic fiber, and method for treating synthetic fiber 竹本油脂株式会社 2022-12-16 CN disclosed
CN-109153908-B Water repellent agent and process for producing the same 明成化学工业株式会社 2021-12-24 CN disclosed
US-20210115357-A1 Fabric Treatment Method for Stain Release VAN BUSKIRK GREGORY (US) 2021-04-22 US disclosed
US-10900168-B2 Fabric treatment for stain repellency van Buskirk, Gregory (US) 2021-01-26 US disclosed
US-10822577-B2 Fabric treatment method for stain release VAN BUSKIRK GREGORY (US) 2020-11-03 US disclosed
EP-0124236-A1 Fluorine-containing copolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-11-07 EP disclosed
US-4362450-A Torque stabilizing method for fasteners and torque stabilized fasteners NIPPON OIL AND FATS CO. LTD. (JP) 1982-12-07 US disclosed
US-4351880-A HOMO-OR COPOLYMERIZING A PERFLUOROALKYL-CONTAINING ACRYLIC OR METHACRYLIC ESTER COATED ON THE WIRE CONNECTOR OF A CONDENSOR DAIKIN KOGYO CO., LTD. (JP) 1982-09-28 US disclosed
US-4299739-A Use of aluminum salts in laundry detergent formulations LEVER BROTHERS COMPANY (US) 1981-11-10 US disclosed
US-4135524-A FLUOROPOLYMER CONTAINING FLUOROALKYL METHACRYLATE, AMINOALKYLMETHACRYLATE AND ETHYLENEDIMETHACRYLATE CLAIROL INCORPORATED (US) 1979-01-23 US disclosed
US-4084059-A OIL REPELLENTS, ANTISOILANTS FOR FIBERS DAIKIN KOGYO CO., LTD. (JA) 1978-04-11 US disclosed
US-4059688-A Hair fixing compositions containing fluoroterpolymers and method CLAIROL INCORPORATED (US) 1977-11-22 US disclosed
US-4032495-A WATER-REPELLENT AND OIL-REPELLENT COMPOSITIONS BASED ON FLUORINE COMPOUND PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-06-28 US disclosed
US-4029585-A SOIL AND FLAME RESISTANCE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-06-14 US disclosed