SCHEMBL12342183

SCHEMBL12342183

CCN(CC)c1ccc(C(c2ccccc2)c2ccc(C)cc2C)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
HTT P42858 2/20 0.44
GAA P10253 1/20 0.44
PKM P14618 1/20 0.44
MCL1 Q07820 1/20 0.44
S100B P04271 1/20 0.44
ALDH1A1 P00352 3/20 0.40
RAB9A P51151 2/20 0.40
CACNA2D1 P54289 3/20 0.39
CACNA1B Q00975 3/20 0.39
CACNB1 Q02641 3/20 0.39
CACNA1C Q13936 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.37
RPS6KA2 Q15349 1/20 0.37
CACNA1G O43497 1/20 0.37
CNR2 P34972 6/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
GRK6 P43250 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133593 0.94 S100B (0.49) MAPTHTTGAAPKMMCL1
SCHEMBL7952524 0.94 S100B (0.49) MAPTHTTGAAPKMMCL1
SCHEMBL10002051 0.91 S100B (0.46) MAPTHTTGAAPKMMCL1
SCHEMBL19886263 0.89 MAPT (0.44) MAPTHTTGAAPKMMCL1
SCHEMBL215745 0.88 S100B (0.49) MAPTHTTGAAPKMMCL1
SCHEMBL29371256 0.88 S100B (0.49) MAPTHTTGAAPKMMCL1
SCHEMBL13649925 0.87 S100B (0.45) MAPTHTTGAAPKMMCL1
SCHEMBL5010117 0.87 S100B (0.45) MAPTHTTGAAPKMMCL1
SCHEMBL10952039 0.86 S100B (0.53) MAPTHTTGAAPKMMCL1
Perchlorate SCHEMBL11345976 0.86 MAPT (0.48) MAPTHTTGAAPKMMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8268521-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-09-18 US disclosed
US-20100151366-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2010-06-17 US disclosed