Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523738 | 0.83 | — | — | |
| SCHEMBL2452696 | 0.83 | — | — | |
| SCHEMBL5377250 | 0.81 | ALDH1A1 (0.46) | TSHRALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL11154934 | 0.81 | TSHR (0.46) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL1682010 | 0.80 | ALDH1A1 (0.43) | TSHRALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL8887970 | 0.79 | TSHR (0.40) | TSHRALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL9407140 | 0.79 | ALDH1A1 (0.38) | TSHRALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL20526062 | 0.79 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL2958422 | 0.77 | CYP3A4 (0.53) | TSHRALDH1A1CYP3A4L3MBTL1 | |
| SCHEMBL21332621 | 0.77 | TSHR (0.50) | TSHRALDH1A1CYP3A4L3MBTL1PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1877099-B1 | THERAPEUTIC CONJUGATES COMPRISING A LYSOSOMAL ENZYME, POLYSIALIC ACID AND A TARGETING MOIETY | GENZYME CORP (US) | 2012-09-19 | — | — | EP | disclosed |