Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14802308 | 0.92 | TOP2A (0.41) | L3MBTL1GAATDP1TOP2AHDAC6 | |
| SCHEMBL12345944 | 0.92 | TOP2A (0.41) | L3MBTL1GAATDP1TOP2AHDAC6 | |
| SCHEMBL15001293 | 0.92 | TOP2A (0.41) | L3MBTL1GAATDP1TOP2AHDAC6 | |
| SCHEMBL15001286 | 0.92 | TOP2A (0.41) | L3MBTL1GAATDP1TOP2AHDAC6 | |
| SCHEMBL15001297 | 0.92 | TOP2A (0.41) | L3MBTL1GAATDP1TOP2AHDAC6 | |
| SCHEMBL15001287 | 0.90 | TOP2A (0.40) | L3MBTL1GAATOP2AHDAC6 | |
| SCHEMBL15001280 | 0.88 | L3MBTL1 (0.40) | L3MBTL1GAATOP2AHDAC6 | |
| SCHEMBL9999550 | 0.86 | KMT2A (0.46) | KMT2AL3MBTL1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL12346024 | 0.86 | KMT2A (0.46) | KMT2AL3MBTL1MAPTHSD17B10ALDH1A1 | |
| SCHEMBL12346026 | 0.86 | KMT2A (0.46) | KMT2AL3MBTL1MAPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189603-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND MANUFACTURING METHOD THEREOF | FUJI ELECTRIC SYSTEMS CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |