SCHEMBL12348993

SCHEMBL12348993

CC(C)(C)c1ccc(-c2cc(-c3cccc4c3sc3ccccc34)ccc2-c2nc3ccccc3n2-c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.40
RECQL P46063 1/20 0.39
MAPK1 P28482 2/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TNKS O95271 2/20 0.37
TNKS2 Q9H2K2 2/20 0.37
TNF P01375 1/20 0.37
NOD1 Q9Y239 1/20 0.37
HTT P42858 1/20 0.36
AKT1 P31749 1/20 0.35
AKT2 P31751 1/20 0.35
AKT3 Q9Y243 1/20 0.35
PTGER4 P35408 1/20 0.35
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
RAB9A P51151 1/20 0.34
PIN1 Q13526 2/20 0.33
PRKDC P78527 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12349409 0.92 ALOX5 (0.46) ALOX5RECQLMAPK1ALDH1A1MAPT
SCHEMBL12348991 0.91 ALOX5 (0.43) ALOX5RECQLMAPK1ALDH1A1MAPT
SCHEMBL12349423 0.91 ALOX5 (0.45) ALOX5RECQLMAPK1ALDH1A1MAPT
SCHEMBL12349396 0.90 ALOX5 (0.42) ALOX5RECQLMAPK1ALDH1A1MAPT
SCHEMBL12567859 0.90 ESR1 (0.42) ALOX5RECQLMAPK1ALDH1A1MAPT
SCHEMBL12568014 0.89 MAPK1 (0.40) ALOX5RECQLMAPK1ALDH1A1MAPT
SCHEMBL12349071 0.89 ALOX5 (0.43) ALOX5RECQLMAPK1ALDH1A1MAPT
SCHEMBL12349669 0.88 ALOX5 (0.42) ALOX5RECQLMAPK1HTTPTGER4
SCHEMBL12567988 0.88 ESR2 (0.41) ALOX5RECQLMAPK1ALDH1A1MAPT
SCHEMBL12349676 0.88 ALOX5 (0.44) ALOX5RECQLMAPK1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2662369-B1 Benzimidazol-2-yl-phenyl compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB (JP) 2015-09-23 EP disclosed
EP-2662369-A1 benzimidazol-2-yl-phenyl compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-11-13 EP disclosed
EP-2354135-B1 Benzimidazol-2-yl-phenyl compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB (JP) 2013-09-18 EP disclosed
US-8354542-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-15 US disclosed
US-8354542-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-15 US disclosed
EP-2354135-A1 benzimidazol-2-yl-phenyl compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-08-10 EP disclosed
US-20110147792-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed
US-20110147792-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110147792-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device CCNE2, CCNE1, CCNT1 ALOX5 1235/4885RECQL 706/4885MAPK1 886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.