SCHEMBL12349193

SCHEMBL12349193

Cc1cc(-c2cccc3c2oc2ccccc23)ccc1-c1nc2ccccc2n1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.46
ALOX5 P09917 2/20 0.45
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
ESR1 P03372 3/20 0.38
ESR2 Q92731 3/20 0.38
RPS6KB1 P23443 2/20 0.38
PRKACA P17612 1/20 0.38
GSK3B P49841 1/20 0.38
ROCK1 Q13464 1/20 0.38
GGPS1 O95749 1/20 0.37
PRKDC P78527 1/20 0.37
PTGER4 P35408 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
RAB9A P51151 1/20 0.36
GRIA1 P42261 1/20 0.35
CACNG8 Q8WXS5 1/20 0.35
CACNG2 Q9Y698 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12567899 0.92 RECQL (0.43) RECQLALOX5MAPK1HTTESR1
SCHEMBL12349449 0.91 ALOX5 (0.46) RECQLALOX5MAPK1HTTESR1
SCHEMBL12349424 0.90 ALOX5 (0.43) RECQLALOX5MAPK1HTTESR1
SCHEMBL12349359 0.90 ALOX5 (0.45) RECQLALOX5MAPK1HTTESR1
SCHEMBL12349436 0.90 RECQL (0.42) RECQLALOX5MAPK1HTTESR1
SCHEMBL12567902 0.89 RECQL (0.43) RECQLALOX5MAPK1HTTESR1
SCHEMBL12567903 0.89 ALOX5 (0.42) RECQLALOX5MAPK1HTTESR1
SCHEMBL12349416 0.89 ALOX5 (0.44) RECQLALOX5MAPK1HTTESR1
SCHEMBL12349235 0.89 ALOX5 (0.40) RECQLALOX5MAPK1HTTESR1
SCHEMBL12567900 0.89 RECQL (0.48) RECQLALOX5MAPK1HTTESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2662369-B1 Benzimidazol-2-yl-phenyl compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB (JP) 2015-09-23 EP disclosed
EP-2662369-A1 benzimidazol-2-yl-phenyl compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-11-13 EP disclosed
EP-2354135-B1 Benzimidazol-2-yl-phenyl compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB (JP) 2013-09-18 EP disclosed
US-8354542-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-15 US disclosed
US-8354542-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-01-15 US disclosed
EP-2354135-A1 benzimidazol-2-yl-phenyl compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-08-10 EP disclosed
US-20110147792-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed
US-20110147792-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110147792-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device and Lighting Device CCNE2, CCNE1, CCNT1 RECQL 706/4885ALOX5 1235/4885MAPK1 886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.