⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2140409 | 0.89 | — | — | |
| SCHEMBL248228 | 0.78 | — | — | |
| SCHEMBL56295 | 0.65 | — | — | |
| SCHEMBL17100739 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL2731248 | 0.62 | — | — | |
| SCHEMBL3632295 | 0.58 | — | — | |
| SCHEMBL25274857 | 0.57 | — | — | |
| SCHEMBL237328 | 0.52 | — | — | |
| SCHEMBL1190870 | 0.52 | — | — | |
| SCHEMBL8853909 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247937-A1 | CYCLOSPORINE ANALOGUES | UCL BUSINESS LTD (GB) | 2023-12-28 | — | — | WO | disclosed |
| EP-3534887-B1 | CANCER THERAPY FOR MIXED LINEAGE LEUKEMIA | UCL BUSINESS LTD (GB) | 2023-09-20 | — | — | EP | disclosed |
| US-20230165964-A1 | Pharmaceutically Active Agent Complexes, Polymer Complexes, and Compositions and Methods Involving the Same | DURECT CORP (US) | 2023-06-01 | — | — | US | disclosed |
| US-20230159593-A1 | CYCLOSPORINE ANALOGUES | UCL BUSINESS LTD (GB) | 2023-05-25 | — | — | US | disclosed |
| EP-4149555-A1 | CYCLOSPORINE ANALOGUES | UCL Business Ltd (GB) | 2023-03-22 | — | — | EP | disclosed |
| US-11529420-B2 | Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same | DURECT CORPORATION (US) | 2022-12-20 | — | — | US | disclosed |
| EP-2773720-B1 | PROCESS FOR TREATING AN UNDERGROUND FORMATION | CLEANSORB LTD (GB) | 2022-07-13 | — | — | EP | disclosed |
| CN-113939544-A | Non-core-shell polymer particles | 悉尼大学 | 2022-01-14 | — | — | CN | disclosed |
| WO-2021229237-A1 | CYCLOSPORINE ANALOGUES | UCL BUSINESS LTD (GB) | 2021-11-18 | — | — | WO | disclosed |
| US-11071720-B2 | Cancer therapy | UCL BUSINESS LTD (GB) | 2021-07-27 | — | — | US | disclosed |
| US-6323207-B1 | TREATMENT OR REDUCTION OF TISSUE DAMAGE DUE TO ISCHAEMIA WHICH COMPRISES ADMINISTERING TO A HOST SUFFERING FROM ISCHAEMIA | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-11-27 | — | — | US | disclosed |
| CN-1072663-C | benzoylguanidine derivatives, process for their preparation and their use in the preparation of pharmaceutical compositions | BOEHRINGER INTELLEIM KG (DE) | 2001-10-10 | — | — | CN | disclosed |
| US-6127423-A | USED IN DISEASES IN WHICH THE LTB4-RECEPTOR-ANTAGONISTIC PROPERTIES PLAY A PART, INCLUDING ARTHRITIS, ASTHMA, CHRONIC OBSTRUCTIVE LUNG DISEASES, E.G., CHRONIC BRONCHITIS, PSORIASIS, ULCERATIVE COLITIS, GASTRO- OR ENTEROPATHY | BOEHRINGER INGELHEIM KG (DE) | 2000-10-03 | — | — | US | disclosed |
| US-6114335-A | Benzoylguanidine derivatives, process for their preparation their use in the preparation of medicines | BOEHRINGER INGELHEIM KG (DE) | 2000-09-05 | — | — | US | disclosed |
| EP-0937041-A1 | PURE ENANTIOMER BASIC ARYL-CYCLOALKYL-HYDROXYCARBOXYLIC ACID ESTERS, PROCESS FOR PREPARING THE SAME AND THEIR USE IN MEDICAMENTS | Noe, Christian R. (DE) | 1999-08-25 | — | — | EP | disclosed |
| CN-1208409-A | Novel benzoyl guanidine derivatives process for their preparation and their use in the preparation of medicines | BOEHRINGER INGELHEIM KG (DE) | 1999-02-17 | — | — | CN | disclosed |
| CN-1204315-A | Novel phenylamidine derivatives, process for preparing same and use thereof as pharmaceutical composition | BOEHRINGER INGELHEIM KG (DE) | 1999-01-06 | — | — | CN | disclosed |
| EP-0882031-A1 | NOVEL BENZOYL GUANIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF MEDICINES | Boehringer Ingelheim Pharma KG (DE) | 1998-12-09 | — | — | EP | disclosed |
| WO-1998021183-A1 | PURE ENANTIOMER BASIC ARYL-CYCLOALKYL-HYDROXYCARBOXYLIC ACID ESTERS, PROCESS FOR PREPARING THE SAME AND THEIR USE IN MEDICAMENTS | NOE CHRISTIAN R (AT) | 1998-05-22 | — | — | WO | disclosed |
| WO-1997026253-A1 | NOVEL BENZOYL GUANIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF MEDICINES | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1997-07-24 | — | — | WO | disclosed |