Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.49 |
| ▸ | RELA | Q04206 | 3/20 | 0.49 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | ACR | P10323 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12347965 | 0.90 | KDM4E (0.51) | NPC1CYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL26226727 | 0.89 | LMNA (0.51) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12669183 | 0.89 | LMNA (0.51) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25501208 | 0.89 | HTT (0.58) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13476135 | 0.89 | NPC1 (0.63) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25491912 | 0.89 | LMNA (0.51) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13476089 | 0.88 | LMNA (0.52) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25773229 | 0.88 | LMNA (0.56) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12354521 | 0.88 | MAPT (0.51) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25501196 | 0.88 | NPC1 (0.52) | NPC1LMNACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998542-B2 | Composition, retardation plate, liquid-crystal display device, and method for producing retardation plate | FUJIFILM CORPORATION (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20090174844-A1 | Composition, Retardation Plate, Liquid-Crystal Display Device, and Method for Producing Retardation Plate | FUJIFILM CORPORATION (JP) | 2009-07-09 | — | — | US | disclosed |