SCHEMBL12354557

SCHEMBL12354557

Cn1c(-c2ccccc2)nc2cc(-c3ccc(-c4ccc5c(-c6cccc7ccccc67)c6ccccc6c(-c6ccc7ccccc7c6)c5c4)cc3)ccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 2/20 0.44
HDAC1 Q13547 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43
PTGER4 P35408 4/20 0.39
ATM Q13315 1/20 0.39
KDM4E B2RXH2 2/20 0.37
NPC1 O15118 2/20 0.37
ALDH1A1 P00352 2/20 0.37
TP53 P04637 2/20 0.37
PKM P14618 2/20 0.37
RAB9A P51151 2/20 0.37
HSD17B10 Q99714 2/20 0.37
GAA P10253 1/20 0.37
ALOX15 P16050 1/20 0.37
F2 P00734 1/20 0.37
F10 P00742 1/20 0.37
PLG P00747 1/20 0.37
PLAU P00749 1/20 0.37
PRSS1 P07477 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12354567 0.95 HDAC1 (0.47) PDE10AHDAC1HDAC8HDAC6PTGER4
SCHEMBL13042945 0.94 PDE10A (0.46) PDE10AHDAC1HDAC8HDAC6PTGER4
SCHEMBL10353573 0.93 PDE10A (0.49) PDE10AHDAC1HDAC8HDAC6PTGER4
SCHEMBL10354063 0.92 PDE10A (0.48) PDE10AHDAC1HDAC8HDAC6PTGER4
SCHEMBL13042939 0.92 PDE10A (0.50) PDE10AHDAC1HDAC8HDAC6PTGER4
SCHEMBL15297871 0.90 PDE10A (0.48) PDE10AHDAC1HDAC8HDAC6PTGER4
SCHEMBL25668090 0.88 PDE10A (0.51) PDE10AHDAC1HDAC8HDAC6PTGER4
SCHEMBL13999971 0.88 HDAC1 (0.53) PDE10AHDAC1HDAC8HDAC6PTGER4
SCHEMBL14363378 0.87 PDE10A (0.47) PDE10AHDAC1HDAC8HDAC6PTGER4
SCHEMBL12354558 0.87 HDAC1 (0.52) PDE10AHDAC1HDAC8HDAC6PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8586202-B2 Organic electroluminescent device and display device SONY CORPORATION (JP) 2013-11-19 US disclosed
US-20110198577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE SONY CORPORATION (JP) 2011-08-18 US disclosed
US-20110198577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE SONY CORPORATION (JP) 2011-08-18 US disclosed
US-20100253214-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2010-10-07 US disclosed
US-20100253214-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2010-10-07 US disclosed