SCHEMBL12354567

SCHEMBL12354567

Cn1c(-c2ccccc2)nc2cc(-c3ccc(-c4ccc5c(-c6cccc7ccccc67)c6ccccc6c(-c6cccc7ccccc67)c5c4)cc3)ccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
PDE10A Q9Y233 1/20 0.45
ATM Q13315 1/20 0.42
PTGER4 P35408 4/20 0.42
ALDH1A1 P00352 3/20 0.40
PKM P14618 3/20 0.40
RAB9A P51151 3/20 0.40
KDM4E B2RXH2 2/20 0.40
NPC1 O15118 2/20 0.40
TP53 P04637 2/20 0.40
HSD17B10 Q99714 2/20 0.40
GAA P10253 1/20 0.40
ALOX15 P16050 1/20 0.40
TLR7 Q9NYK1 1/20 0.40
F2 P00734 1/20 0.40
F10 P00742 1/20 0.40
PLG P00747 1/20 0.40
PLAU P00749 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13042945 0.99 PDE10A (0.46) HDAC1HDAC8HDAC6PDE10AATM
SCHEMBL12354557 0.95 PDE10A (0.44) HDAC1HDAC8HDAC6PDE10AATM
SCHEMBL15297871 0.93 PDE10A (0.48) HDAC1HDAC8HDAC6PDE10AATM
SCHEMBL12354561 0.91 HDAC1 (0.49) HDAC1HDAC8HDAC6PDE10AATM
SCHEMBL13042944 0.90 PDE10A (0.47) HDAC1HDAC8HDAC6PDE10AATM
SCHEMBL12354558 0.89 HDAC1 (0.52) HDAC1HDAC8HDAC6PDE10AATM
SCHEMBL3748961 0.88 HDAC1 (0.53) HDAC1HDAC8HDAC6PDE10AATM
SCHEMBL10354051 0.87 PDE10A (0.49) HDAC1HDAC8HDAC6PDE10AATM
SCHEMBL3738165 0.87 HDAC1 (0.51) HDAC1HDAC8HDAC6PDE10AATM
SCHEMBL13043014 0.87 HDAC1 (0.54) HDAC1HDAC8HDAC6PDE10AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8586202-B2 Organic electroluminescent device and display device SONY CORPORATION (JP) 2013-11-19 US disclosed
US-20110198577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE SONY CORPORATION (JP) 2011-08-18 US disclosed
US-20110198577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE SONY CORPORATION (JP) 2011-08-18 US disclosed
US-20100253214-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2010-10-07 US disclosed
US-20100253214-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2010-10-07 US disclosed