SCHEMBL12354568

SCHEMBL12354568

Cc1nc2cc(-c3ccc(-c4ccc5c(-c6ccccc6-c6ccccc6)c6ccccc6c(-c6ccccc6-c6ccccc6)c5c4)cc3)ccc2n1-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
HSD17B10 Q99714 2/20 0.47
HTT P42858 2/20 0.47
MAPK1 P28482 1/20 0.47
KDM4E B2RXH2 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPC1 O15118 1/20 0.44
PTGER4 P35408 1/20 0.39
MCHR1 Q99705 1/20 0.38
MGLL Q99685 2/20 0.38
AVPR1A P37288 1/20 0.37
THRB P10828 1/20 0.37
TSHR P16473 1/20 0.37
PIK3CD O00329 1/20 0.37
PIK3CA P42336 1/20 0.37
MTOR P42345 1/20 0.37
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
ATM Q13315 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14499578 0.93 ALDH1A1 (0.54) ALDH1A1HSD17B10HTTMAPK1KDM4E
SCHEMBL13042713 0.91 ALDH1A1 (0.54) ALDH1A1HSD17B10HTTMAPK1KDM4E
SCHEMBL14499581 0.90 ALDH1A1 (0.51) ALDH1A1HSD17B10HTTMAPK1KDM4E
SCHEMBL13042708 0.90 PTGER4 (0.44) ALDH1A1HSD17B10HTTPTGER4AVPR1A
SCHEMBL18999424 0.90 ALDH1A1 (0.53) ALDH1A1HSD17B10HTTMAPK1KDM4E
SCHEMBL13042816 0.89 ALDH1A1 (0.56) ALDH1A1HSD17B10HTTMAPK1KDM4E
SCHEMBL13042873 0.89 ALDH1A1 (0.56) ALDH1A1HSD17B10HTTMAPK1KDM4E
SCHEMBL13042812 0.88 ESR1 (0.43) ALDH1A1HSD17B10HTTPTGER4AVPR1A
SCHEMBL13042870 0.88 PTGER4 (0.44) ALDH1A1HSD17B10HTTPTGER4TSHR
SCHEMBL13043013 0.88 ESR1 (0.43) ALDH1A1HSD17B10HTTPTGER4AVPR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8586202-B2 Organic electroluminescent device and display device SONY CORPORATION (JP) 2013-11-19 US disclosed
US-20110198577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE SONY CORPORATION (JP) 2011-08-18 US disclosed
US-20110198577-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND DISPLAY DEVICE SONY CORPORATION (JP) 2011-08-18 US disclosed
US-20100253214-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2010-10-07 US disclosed
US-20100253214-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY DEVICE SONY CORPORATION (JP) 2010-10-07 US disclosed